METTL4 is an snRNA m6Am methyltransferase that regulates RNA splicing

  • Cell Res. 2020 Jun;30(6):544-547. doi: 10.1038/s41422-019-0270-4.
Hao Chen  #  1 ,  Lei Gu  #  1 ,  Esteban A Orellana  2 ,  Yuanyuan Wang  3 ,  Jiaojiao Guo  4 ,  Qi Liu  2 ,  Longfei Wang  5  6 ,  Zhangfei Shen  1  5  6 ,  Hao Wu  5  6 ,  Richard I Gregory  2 ,  Yi Xing  7  8 ,  Yang Shi  9
Affiliations
  • 1. Division of Newborn Medicine and Program in Epigenetics, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA, 02115, USA.
  • 2. Stem Cell Program, Division of Hematology/Oncology, Boston Children's Hospital, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, 02115, USA.
  • 3. Bioinformatics Interdepartmental Graduate Program, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
  • 4. College of Science, Northeastern University, 360 Huntington Ave., Boston, MA, 02115, USA.
  • 5. Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, 02115, USA.
  • 6. Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, 02115, USA.
  • 7. Center for Computational and Genomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
  • 8. Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • 9. Division of Newborn Medicine and Program in Epigenetics, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA, 02115, USA. [email protected].
  • # Contributed equally.
PMID: 31913360 DOI: 10.1038/s41422-019-0270-4