NR4A1 suppresses pyroptosis by transcriptionally inhibiting NLRP3 and IL-1β and co-localizing with NLRP3 in trans-Golgi to alleviate pathogenic bacteria-induced colitis

Zhao Deng  ¹ ,  Zhipeng Yang  ¹ ,  Chenbin Cui  ¹ ,  Hongkui Wei  ¹ ,  Lijia Wang  ² ,  Dean Tian  ² ,  Fang Xiao  ² ,  Jian Peng  ^{1  3}