Novel Nonpeptide as Oxytocin Receptor Agonist

  • ACS Med Chem Lett. 2025 Apr 21;16(5):750-751. doi: 10.1021/acsmedchemlett.5c00191.
Yinlong Li  1 ,  Steven H Liang  1
Affiliations
  • 1. Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States.
PMID: 40365388 DOI: 10.1021/acsmedchemlett.5c00191
Abstract

This highlight describes a series of novel 1,4-benzodiazepine-based nonpeptides as Oxytocin Receptor (OT) agonists. The reported compounds demonstrate enhanced potency and selectivity compared to reference compounds, warranting further investigation for potential therapeutic applications in the treatment of OT-related pathologies.

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