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Cat. No.: HY-101474BR

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(R)-Zanubrutinib (Standard)

(Synonyms: (R)-BGB-3111 (Standard))

(R)-Zanubrutinib (Standard) is the analytical standard of (R)-Zanubrutinib (HY-101474B). This product is intended for research and analytical applications. (R)-Zanubrutinib is the R enantiomer of Zanubrutinib (HY-101474A). (R)-Zanubrutinib inhibits Bruton's tyrosine kinase (Btk) with an IC50 of 11 nM.

For research use only. We do not sell to patients.

Purity: 98%
CAS No.: 1691249-44-1
Formula: C₂₇H₂₉N₅O₃
Molecular Weight:471.55

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

(R)-Zanubrutinib (Standard) Chemical Structure

CAS No.: 1691249-44-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 1691249-44-1
Molecular Weight 471.55
Formula C₂₇H₂₉N₅O₃
SMILES

NC(C1=C2N(N=C1C3=CC=C(OC4=CC=CC=C4)C=C3)[C@@H](C5CCN(C(C=C)=O)CC5)CCN2)=O
Synonyms

(R)-BGB-3111 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Wu J, et al. Acalabrutinib (ACP-196): a selective second-generation BTK inhibitor. J Hematol Oncol. 2016 Mar 9;9:21. [Content Brief]

[2]. Wu J, et al. Second-generation inhibitors of Bruton tyrosine kinase. J Hematol Oncol. 2016 Sep 2;9(1):80. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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