2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. GlyT
  4. (Rac)-ALX 5407

NFPS is a selective, non-competitive glycine transporter-1 (GlyT1) inhibitor with IC50s of 2.8 nM and 9.8 nM for hGlyT1 and rGlyT1, respectively. NFPS exerts neuroprotection via glyR alpha1 subunit in the rat model of transient focal cerebral ischaemia and reperfusion.

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(Rac)-ALX 5407

(Rac)-ALX 5407 Estructura química

No. CAS : 405225-21-0

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(Rac)-ALX 5407 Related Antibodies

Top Publications Citing Use of Products

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GlyT1 GlyT2

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Descripciòn

NFPS is a selective, non-competitive glycine transporter-1 (GlyT1) inhibitor with IC50s of 2.8 nM and 9.8 nM for hGlyT1 and rGlyT1, respectively[1]. NFPS exerts neuroprotection via glyR alpha1 subunit in the rat model of transient focal cerebral ischaemia and reperfusion[2].

IC50 & Target[1]

hGlyT1

2.8 nM (IC50)

rGlyT1

9.8 nM (IC50)

Peso molecular

393.45

Fòrmula

C24H24FNO3
No. CAS
SMILES

OC(CN(C)CCC(C1=CC=C(F)C=C1)OC2=CC=C(C3=CC=CC=C3)C=C2)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

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Referencias
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(Rac)-ALX 5407 Related Classifications

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Keywords:

(Rac)-ALX 5407405225-21-0(Rac)-NFPSGlyTGlycine transportersInhibitorinhibitorinhibit

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