1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. GlyT
  3. GlyT1 Inhibitor 1

GlyT1 Inhibitor 1 

Cat. No.: HY-112432
Handling Instructions

GlyT1 Inhibitor 1 is a potent and selective GlyT1 inhibitor with an IC50 of 38 nM for rGlyT1. Antipsychotic activity.

For research use only. We do not sell to patients.

GlyT1 Inhibitor 1 Chemical Structure

GlyT1 Inhibitor 1 Chemical Structure

CAS No. : 1820934-93-7

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Description

GlyT1 Inhibitor 1 is a potent and selective GlyT1 inhibitor with an IC50 of 38 nM for rGlyT1[1]. Antipsychotic activity[1].

IC50 & Target

rGlyT1

38 nM (IC50)

In Vivo

GlyT1 Inhibitor 1 (Compound 46) demonstrates in vivo efficacy in a rat novel object recognition (NOR) assay after oral dosing at 0.1, 1, and 3 mg/kg[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

387.43

Formula

C₂₂H₂₁N₅O₂

CAS No.

1820934-93-7

SMILES

CC(C)OC1=C(C(N2CC3=CN(C4=CC(C)=NC=C4)N=C3C2)=O)C=C(C#N)C=C1

Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
GlyT1 Inhibitor 1
Cat. No.:
HY-112432
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GlyT1 Inhibitor 1

Cat. No.: HY-112432