2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
    Neuronal Signaling
  4. GlyT
  5. GlyT1 Isoform
  6. GlyT1 Inhibitor

GlyT1 Inhibitor

GlyT1 Inhibitors (6):

Cat. No. Product Name Effect Purity
  • HY-138935
    Iclepertin
    		Inhibitor 99.65%
    Iclepertin (BI-425809) is a potent, selective and orally active glycine transporter 1 (GlyT1) inhibitor.
  • HY-100416A
    LY2365109 hydrochloride
    		Inhibitor 98.69%
    LY2365109 hydrochloride is a potent and selective GlyT1 inhibitor, with an IC50 of 15.8 nM for glycine uptake in cells over-expressing hGlyT1a.
  • HY-112432
    GlyT1 Inhibitor 1
    		Inhibitor 98.35%
    GlyT1 Inhibitor 1 is a potent and selective GlyT1 inhibitor with an IC50 of 38 nM for rGlyT1.
  • HY-10715
    SSR504734
    		Inhibitor 99.82%
    SSR504734 is an orally active, selective and reversible inhibitor of human, rat, and mouse GlyT1 (IC50=18, 15, and 38 nM, respectively).
  • HY-107526
    (Rac)-ALX 5407
    		Inhibitor
    NFPS is a selective, non-competitive glycine transporter-1 (GlyT1) inhibitor with IC50s of 2.8 nM and 9.8 nM for hGlyT1 and rGlyT1, respectively.
  • HY-122666
    Org 25935
    		Inhibitor
    Org 25935 is a potent and selective glycine transporter 1 protein (GlyT1) inhibitor with an IC50 value of 100 nM.