GSK494581A
GSK494581A is a specific ligand for human GPR55 (pEC50 of 6.8) and also acts as an inhibitor of glycine transporter subtype 1 (GlyT1). GSK494581A may regulate pain signaling, bone morphogenesis, and vascular endothelial cell formation by binding to GPR55.
For research use only. We do not sell to patients.
- CAS No.: 909416-67-7
- Formula: C27H28F2N2O4S
- Molecular Weight:514.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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rGlyT1 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
20 nM
Compound: GSK494581A
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Inhibition of GlyT1 (unknown origin) expressed in HEK293 cells by scintillation proximity assay
Inhibition of GlyT1 (unknown origin) expressed in HEK293 cells by scintillation proximity assay
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[PMID: 26575458] |
Chemical Information
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CAS No. 909416-67-7
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Molecular Weight 514.58
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Formula C27H28F2N2O4S
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SMILES
O=C(N1CCN(C2=CC=C(C(OC)C)C=C2F)CC1)C3=CC(S(=O)(C)=O)=CC=C3C4=CC=C(F)C=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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