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ADH6 Protein, Human

The ADH6 protein is considered an alcohol dehydrogenase and is critical in cellular metabolism. It catalyzes the NAD-dependent oxidation of primary alcohols to aldehydes and promotes the oxidation of secondary alcohols to ketones. ADH6 Protein, Human is the recombinant human-derived ADH6 protein, expressed by E. coli , with tag free.

For research use only. We do not sell to patients.
  • Species: Human
  • Source: E. coli
  • ADH6 Protein, Human Product Image
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Biological Activity

Description

The ADH6 protein is considered an alcohol dehydrogenase and is critical in cellular metabolism. It catalyzes the NAD-dependent oxidation of primary alcohols to aldehydes and promotes the oxidation of secondary alcohols to ketones. ADH6 Protein, Human is the recombinant human-derived ADH6 protein, expressed by E. coli , with tag free.

Background

ADH6, identified as alcohol dehydrogenase, plays a crucial role in cellular metabolism by catalyzing the NAD-dependent oxidation of primary alcohols to their respective aldehydes and facilitating the oxidation of secondary alcohols to the corresponding ketones. The enzyme's activity is vital in alcohol metabolism, contributing to the conversion of diverse alcohol substrates in cellular processes. Through its catalytic function, ADH6 participates in maintaining cellular redox balance and is integral to the intricate network of alcohol-related metabolic pathways.

Technical Parameters

  • Species Human
  • Source E. coli
  • Tag Tag Free
  • Accession

    P28332 (M1-W368)

  • Gene ID
    130
  • Molecular Construction
    • N-term
    • ADH6 (M1-W368)
      Accession # P28332
    • C-term
  • Protein Length

    Full Length

  • Synonyms

    ADH6; Alcohol dehydrogenase 6

  • AA Sequence

    MSTTGQVIRCKAAILWKPGAPFSIEEVEVAPPKAKEVRIKVVATGLCGTEMKVLGSKHLDLLYPTILGHEGAGIVESIGEGVSTVKPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQSKTQLMSDGTSRFTCKGKSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFSTGFGAAINTAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGATECLNPQDLKKPIQEVLFDMTDAGIDFCFEAIGNLDVLAAALASCNESYGVCVVVGVLPASVQLKISGQLFFSGRSLKGSVFGGWKSRQHIPKLVADYMAEKLNLDPLITHTLNLDKINEAVELMKTGKW

  • Purity

    ≥ 90%, as determined by reducing SDS-PAGE.

Calculators

Reconstitution Calculator

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The Specific Activity Calculator Equation
  • Specific Activity (Unit/mg)
  • Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) Specific Activity (Unit/mg)
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MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

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