GARP&Latent TGF Beta 1 Complex Protein, Human (Biotinylated, HEK293, His-Avi)

GARP is a transmembrane protein that acts as a docking receptor for potential transforming growth factor (LTGF-β) and plays a key role in the production and release of active transforming growth factor β (TGF-β). The presence of GARP affects immune-mediated diseases such as cancer, allergies, and autoimmunity. GARP&Latent TGF Beta 1 Complex Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing rat-derived GARP&Latent TGF Beta 1 Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. GARP&Latent TGF Beta 1 Complex Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of 70-80 kDa (GARP) & 42-48 kDa & 13 kDa (L, respectively.

GARP is a transmembrane protein that acts as a docking receptor for potential transforming growth factor (LTGF-β) and plays a key role in the production and release of active transforming growth factor β (TGF-β). The presence of GARP as a soluble factor and surface marker for different cell types affects immune-mediated diseases such as cancer, allergies, and autoimmunity. GARP can be used as a biomarker and therapeutic target^[1][2].

Rat

HEK293

C-Avi;C-8*His

D3ZVD5 (I18-N628)&P17246 (L30-R278)

293135&59086

Biotin

The single lysine residue in Avitag is biotinylated through an enzymatic reaction.

Approximately 70-80 kDa (GARP) & 42-48 kDa & 13 kDa (Latent TGF beta 1),based on SDS-PAGE under reducing conditions,due to the glycosylation.

≥ 95%, as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.