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IMPDH1 Protein, Human

IMPDH1 Protein, Human is the recombinant human-derived IMPDH1, expressed by E. coli , with tag Free labeled tag. ,

For research use only. We do not sell to patients.
  • Species: Human
  • Source: E. coli
  • IMPDH1 Protein, Human Product Image
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
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Biological Activity

Description

IMPDH1 Protein, Human is the recombinant human-derived IMPDH1, expressed by E. coli , with tag Free labeled tag. ,

Background

IMPDH1 catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, thus playing a key role in regulating cell growth. It may also possess single-stranded nucleic acid-binding activity and could be involved in RNA and/or DNA metabolism. Additionally, IMPDH1 might contribute to malignancy development and tumor progression. by similar: This description is inferred from the functions of similar proteins.

Technical Parameters

  • Species Human
  • Source E. coli
  • Tag Tag Free
  • Accession

    P20839-1 (M1-Y514)

  • Gene ID
    3614
  • Protein Length

    Full Length of Isoform-1

  • Synonyms

    IMPDH1; IMPD 1; Prev. RP10; IMPD; SWSS2608; Retinitis Pigmentosa 10 (Autosomal Dominant); LCA11; IMP (Inosine Monophosphate) Dehydrogenase 1; IMP (Inosine 5'-Monophosphate) Dehydrogenase 1; Inosine-5'-Monophosphate Dehydrogenase; Inosine-5'-Monophosphate

  • AA Sequence

    MADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY

  • Predicted Molecular Mass

    55.6 kDa

  • Purity

    ≥ 85%, as determined by reducing SDS-PAGE.

Calculators

Reconstitution Calculator

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The Specific Activity Calculator Equation
  • Specific Activity (Unit/mg)
  • Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

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MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • IMPDH1 Protein, Human Product Image