ROM1 Protein, Human (His)

ROM1 protein is involved in rod outer segment (ROS) morphogenesis, and may work with PRPH2 to maintain the structure of the curved intervertebral disc and organize ROS, thus affecting the intervertebral disc diameter. In addition, ROM1 is involved in protecting the retinal outer nuclear layer. ROM1 Protein, Human (His) is the recombinant human-derived ROM1 protein, expressed by E. coli , with N-His labeled tag. The total length of ROM1 Protein, Human (His) is 138 a.a., with molecular weight of ~18 kDa.

ROM1 protein is implicated in rod outer segment (ROS) morphogenesis and, in collaboration with PRPH2, contributes to maintaining the structure of curved disks within the ROS. Additionally, it plays a vital role in organizing the ROS and preserving the diameter of its disks. Beyond its role in the visual system, ROM1 is involved in maintaining the outer nuclear layer of the retina. It forms homodimers and homotetramers, with the latter participating in higher-order complex formation through intermolecular disulfide bonds. ROM1 also forms heterotetramers with PRPH2 and interacts with proteins such as STX3 and SNAP25, suggesting its involvement in complex cellular processes.

Human

E. coli

N-His

Q03395 (P126-D263)

6094  [NCBI]

Approximately 18 kDa

Greater than 85% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.