1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. EGF Superfamily
  4. TGF-alpha
  5. TGF alpha/TGFA Protein, Human (CHO)

TGF alpha/TGFA Protein, Human (CHO)

Cat. No.: HY-P7296
COA Handling Instructions

TGF-alpha Protein, Human (CHO) is a potent angiogenic mediator and mitogenic polypeptide.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μg $70 In-stock
50 μg $160 In-stock
100 μg   Get quote  
250 μg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

  • References


TGF-alpha Protein, Human (CHO) is a potent angiogenic mediator and mitogenic polypeptide.


Transforming growth factors (TGF's) are polypeptides that can confer phenotypic transformation to several normal cells. TGF-α binds to the receptor for epidermal growth factor (EGF) and has been isolated from a variety of tumor cells. TGF-α is synthesized in embryos during early fetal development, in several virally transformed cells, and in a large variety of human tumors[1]. TGF-α is a member of the epidermal growth factor family of mitogens and associated with progression of transformed properties in human colon cancer cells[2].

Biological Activity

The ED50 is <0.4 ng/mL as measured by 3T3 cells.






Tag Free


P01135 (V40-A89)

Gene ID
AA Sequence


Molecular Weight

8-10 kDa


Greater than 95% as determined by reducing SDS-PAGE.


Lyophilized powder.


Lyophilized after extensive dialysis against PBS.

Endotoxin Level

<0.2 EU/μg, determined by LAL method.


It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Storage & Stability

Stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.


Room temperature in continental US; may vary elsewhere.


TGF alpha/TGFA Protein, Human (CHO) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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