1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. EGF superfamily
  4. TGF-alpha
  5. TGF-alpha Protein, Human (CHO)

TGF-alpha Protein, Human (CHO)

Cat. No.: HY-P7296
Handling Instructions

TGF-alpha Protein, Human (CHO) is a potent angiogenic mediator and mitogenic polypeptide.

For research use only. We do not sell to patients.

Protein Expression Service

Recombinant Proteins-MedChemExpress
Size Price Stock Quantity
10 μg $70 In-stock
Estimated Time of Arrival: December 31
50 μg $160 In-stock
Estimated Time of Arrival: December 31
100 μg   Get quote  
250 μg   Get quote  

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TGF-alpha Protein, Human (CHO) Related Classifications

  • Technical Parameters

  • Properties

  • Documentation

Species

Human

Source

CHO

Tag

Tag Free

Accession

P01135 (V40-A89)

Gene ID

7039

Synonyms
rHuTGF-α; ETGF; TGFA
AA Sequence

VVSHFNDCPDSHTQFCFHGTCRFLVQEDKPACVCHSGYVGARCEHADLLA

Molecular Weight

8-10 kDa

Biological Activity
The ED50 is <0.4 ng/mL as measured by 3T3 cells.
Appearance

Lyophilized powder.

Formulation

Lyophilized after extensive dialysis against PBS.

Endotoxin Level

<0.2 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O or PBS.

Storage & Stability

Stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Background

Transforming growth factors (TGF's) are polypeptides that can confer phenotypic transformation to several normal cells. TGF-α binds to the receptor for epidermal growth factor (EGF) and has been isolated from a variety of tumor cells. TGF-α is synthesized in embryos during early fetal development, in several virally transformed cells, and in a large variety of human tumors[1]. TGF-α is a member of the epidermal growth factor family of mitogens and associated with progression of transformed properties in human colon cancer cells[2].

Documentation
References
  • Reconstitution Calculator

  • Dilution Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
TGF-alpha Protein, Human (CHO)
Cat. No.:
HY-P7296
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