Rizatriptan hemisulfate hemihydrate
Rizatriptan (MK 462) hemisulfate hemihydrate is the agonist for 5-HT1B and 5-HT1D. Rizatriptan hemisulfate hemihydrate has a peripheral vasoconstrictive effect, penetrates the intact blood-brain barrier, and inhibits pain neurotransmission in the central nervous system.
For research use only. We do not sell to patients.
- CAS No.: 159776-67-7
- Formula: C15H19N5.1/2H2O4S.1/2H2O
- Molecular Weight:327.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All 5-HT Receptor Isoforms
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Biological Activity
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5-HT1B Receptor |
5-HT1D Receptor |
Chemical Information
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CAS No. 159776-67-7
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Molecular Weight 327.39
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Formula C15H19N5.1/2H2O4S.1/2H2O
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SMILES
O=S(O)(O)=O.CN(C)CCC1=CNC2=C1C=C(C=C2)CN3N=CN=C3.O.[1/2].[1/2]
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Synonyms
MK 462 hemisulfate hemihydrate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Sciberras DG, et al. Initial human experience with MK-462 (rizatriptan): a novel 5-HT1D agonist. Br J Clin Pharmacol. 1997 Jan;43(1):49-54. [Content Brief]
[2]. Cumberbatch MJ, et al. Rizatriptan has central antinociceptive effects against durally evoked responses. Eur J Pharmacol. 1997 Jun 5;328(1):37-40. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Rizatriptan hemisulfate hemihydrate Related Classifications
HY-W018475B Related Classifications
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