Ro 04-6790 dihydrochloride
Ro 04-6790 dihydrochloride is a potent, competitive and selective 5-HT6 receptor antagonist with pKi values of 7.26, 7.35 for rat and human 5-HT6 receptors, respectively. Ro 04-6790 dihydrochloride has no affinity at other receptors.
For research use only. We do not sell to patients.
- CAS No.: 1197333-95-1
- Formula: C12H18Cl2N6O2S
- Molecular Weight:381.28
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All 5-HT Receptor Isoforms
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Biological Activity
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5-HT6 Receptor |
Chemical Information
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CAS No. 1197333-95-1
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Molecular Weight 381.28
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Formula C12H18Cl2N6O2S
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SMILES
O=S(C1=CC=C(C=C1)N)(NC2=NC(NC)=NC(NC)=C2)=O.[H]Cl.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. A J Sleight, et al. Characterization of Ro 04-6790 and Ro 63-0563: potent and selective antagonists at human and rat 5-HT6 receptors. Br J Pharmacol. 1998 Jun;124(3):556-62. [Content Brief]
[2]. Sudabeh Shirazi-Southall, et al. Effects of typical and atypical antipsychotics and receptor selective compounds on acetylcholine efflux in the hippocampus of the rat. Neuropsychopharmacology. 2002 May;26(5):583-94. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ro 04-6790 dihydrochloride Related Classifications
HY-14335A Related Classifications
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