234 Results for "

nanoparticles modification

" in MedChemExpress (MCE) Product Catalog:
Products (234)

234 Results for "nanoparticles modification" in MCE Product Catalog:

Cat. No.: HY-185404
Target:  

Liposome

Research Areas:  

Others

DSPE-PEG8-OH is a monodisperse lipid-polyethylene glycol conjugate featuring a hydrophobic 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE) anchor, an 8-unit discrete (PEG8) spacer, and a terminal hydroxyl (-OH) group. DSPE-PEG8-OH is primarily used in liposome formulation, nanoparticle surface modification, and targeted drug delivery systems.
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Cat. No.: HY-187402A
Research Areas:  

Cancer

DOPE-PEG2000-CSTSMLKAC is an amphiphilic lipid-PEG-peptide conjugate composed of DOPE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine), PEG2000, and the CSTSMLKAC peptide, a cyclic tumor-homing peptide with a disulfide bond formed by flanking cysteine residues. DOPE-PEG2000-CSTSMLKAC is used for tumor-targeted drug delivery through liposome and nanoparticle surface modification.
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Cat. No.: HY-188101
Target:  

mRNA

Research Areas:  

Cancer

CD19 CAR mRNA (Human)-LNP is a lipid nanoparticle (LNP) encapsulating CD19 CAR mRNA (Human). CD19 CAR mRNA (Human) can express a CAR protein targeting human CD19. CD19 CAR mRNA can trigger transient CAR expression, allowing T cells to be targeted without permanent genetic modification. CD19 CAR mRNA can be used in cancer research such as lymphoma and leukemia.
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Cat. No.: HY-P11886
Synonyms: GNYTCEVTELTREGETIIELK-Azide
Research Areas:  

Others

GNYTCEVTELTREGETIIELK-N3 (GNYTCEVTELTREGETIIELK-Azide) is a conjugate of an azide (-N3) group and a CD47 functional peptide (GNYTCEVTELTREGETIIELK). Modifying the surface of LNPs with GNYTCEVTELTREGETIIELK significantly reduces the recognition and clearance of LNPs by the mononuclear phagocytic system (MPS) and reduces their accumulation in non-target tissues such as the liver and spleen. The azide group in GNYTCEVTELTREGETIIELK-N3 can undergo click chemistry reactions for applications such as constructing targeted drug delivery systems and nanoparticle modification.
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Cat. No.: HY-187416A
Synonyms: DOPE-PEG2000-Mal-Cys-CGKRK
Research Areas:  

Cancer

DOPE-PEG2000-CGKRK (DOPE-PEG2000-Mal-Cys-CGKRK) is an amphiphilic lipid-PEG-peptide conjugate consisting of DOPE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine), PEG2000, and the CGKRK peptide, a tumor-homing peptide identified by in vivo phage display. DOPE-PEG2000-CGKRK is used for tumor-targeted drug delivery through liposome and nanoparticle surface modification.
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Cat. No.: HY-187492A
Synonyms: DOPE-PEG2000-Mal-CKAAKNK
Research Areas:  

Others

DOPE-PEG2000-KAA (DOPE-PEG2000-Mal-CKAAKNK) is an amphiphilic lipid-PEG-peptide conjugate composed of DOPE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine), PEG2000, and the KAA peptide. KAA peptide functions as a targeting ligand for specific cell or tissue recognition. DOPE-PEG2000-KAA is used for targeted drug delivery through liposome and nanoparticle surface modification.
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Cat. No.: HY-187493A
Synonyms: DOPE-PEG2000-Mal-Cys-DHLASLWWGTEL
Research Areas:  

Others

DOPE-PEG2000-DHLASLWWGTEL (DOPE-PEG2000-Mal-Cys-DHLASLWWGTEL) is an amphiphilic lipid-PEG-peptide conjugate composed of DOPE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine), PEG2000, and the DHLASLWWGTEL peptide, a 12-amino-acid tissue-targeting peptide identified through phage display. DOPE-PEG2000-DHLASLWWGTEL is used for targeted drug delivery through liposome and nanoparticle surface modification.
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Cat. No.: HY-W1049002
3-Arm PEG2000-Mal is a three-armed PEG derivative. The core structure of 3-Arm PEG2000-Mal consists of three PEG chains, each terminal of which is modified with a maleimide (Mal) group. The maleimide group in 3-Arm PEG2000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-W1049002A
3-Arm PEG5000-Mal is a three-armed PEG derivative. The core structure of 3-Arm PEG5000-Mal consists of three PEG chains, each terminal of which is modified with a maleimide (Mal) group. The maleimide group in 3-Arm PEG5000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-W1049002B
3-Arm PEG10000-Mal is a three-armed PEG derivative. The core structure of 3-Arm PEG10000-Mal consists of three PEG chains, each terminal of which is modified with a maleimide (Mal) group. The maleimide group in 3-Arm PEG10000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-W1049002C
3-Arm PEG20000-Mal is a three-armed PEG derivative. The core structure of 3-Arm PEG20000-Mal consists of three PEG chains, each terminal of which is modified with a maleimide (Mal) group. The maleimide group in 3-Arm PEG20000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-W1049002D
3-Arm PEG40000-Mal is a three-armed PEG derivative. The core structure of 3-Arm PEG40000-Mal consists of three PEG chains, each terminal of which is modified with a maleimide (Mal) group. The maleimide group in 3-Arm PEG40000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-W1048914
3-Arm PEG2000-NH2 is a three-armed PEG derivative. The core structure of 3-Arm PEG2000-NH2 consists of three PEG chains, each terminal of which is modified with an amino (-NH2) group. The primary amino group in 3-Arm PEG2000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-W1048914A
3-Arm PEG5000-NH2 is a three-armed PEG derivative. The core structure of 3-Arm PEG5000-NH2 consists of three PEG chains, each terminal of which is modified with an amino (-NH2) group. The primary amino group in 3-Arm PEG5000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-W1048914B
3-Arm PEG10000-NH2 is a three-armed PEG derivative. The core structure of 3-Arm PEG10000-NH2 consists of three PEG chains, each terminal of which is modified with an amino (-NH2) group. The primary amino group in 3-Arm PEG10000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-W1048914C
3-Arm PEG20000-NH2 is a three-armed PEG derivative. The core structure of 3-Arm PEG20000-NH2 consists of three PEG chains, each terminal of which is modified with an amino (-NH2) group. The primary amino group in 3-Arm PEG20000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-W1048914D
3-Arm PEG40000-NH2 is a three-armed PEG derivative. The core structure of 3-Arm PEG40000-NH2 consists of three PEG chains, each terminal of which is modified with an amino (-NH2) group. The primary amino group in 3-Arm PEG40000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-176522
Research Areas:  

Cancer

Oligomer-lipid 7C1 is an ionazable lipid. Oligomer-lipid 7C1 can be generated through the reaction of low-molecular-weight polyamine with lipid. Oligomer-lipid 7C1 efficiently binds siRNA to form nanoparticle. Oligomer-lipid 7C1 can induce RNA interference in endothelial cells of multiple organs in nonhuman primates. Oligomer-lipid 7C1 is able to deliver siRNA to endothelial cells and facilitates endothelial function modification in mouse models of vascular permeability, emphysema, primary tumor growth and metastasis .
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Cat. No.: HY-W1049011
3-Arm PEG2000-SG is a three-armed PEG derivative. The core structure of 3-Arm PEG2000-SG consists of three PEG chains, each terminal of which is modified with a succinimide glutarate (-SG) group. The succinimide glutarate in 3-Arm PEG2000-SG can undergo rapid addition reactions with molecules containing primary amine groups to form stable amide bonds, which can be used in applications such as constructing targeted drug delivery systems and nanoparticle modification.
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Cat. No.: HY-W1049011A
3-Arm PEG5000-SG is a three-armed PEG derivative. The core structure of 3-Arm PEG5000-SG consists of three PEG chains, each terminal of which is modified with a succinimide glutarate (-SG) group. The succinimide glutarate in 3-Arm PEG5000-SG can undergo rapid addition reactions with molecules containing primary amine groups to form stable amide bonds, which can be used in applications such as constructing targeted drug delivery systems and nanoparticle modification.
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