3-Arm PEG5000-NH2
3-Arm PEG5000-NH2 is a three-armed PEG derivative. The core structure of 3-Arm PEG5000-NH2 consists of three PEG chains, each terminal of which is modified with an amino (-NH2) group. The primary amino group in 3-Arm PEG5000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
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- Masse moléculaire:5000 (Average)
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
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Help & FAQs
Activité biologique
The structure of PEG-NH2 contains two key parts that work synergistically:
Primary amino group (-NH2): Located at the end of the PEG chain, it is a reaction interface that can couple with various molecules through a mild and efficient chemical method such as amidation.
PEG chain: As a hydrophilic spacer, it forms a hydration layer on the particle surface, reducing non-specific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Masse moléculaire 5000 (Average)
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SMILES
CCC(COCCOCCN)(COCCOCCN)COCCOCCN.[n].[n].[n]
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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