3-Arm PEG2000-Mal
3-Arm PEG2000-Mal is a three-armed PEG derivative. The core structure of 3-Arm PEG2000-Mal consists of three PEG chains, each terminal of which is modified with a maleimide (Mal) group. The maleimide group in 3-Arm PEG2000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Masse moléculaire:2000 (Average)
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
In Vitro
The structure of PEG-Alkyne comprises two key components that work synergistically:
Maleimide: Located at the end of the PEG chain, it acts as a reaction interface, enabling specific Michael addition reactions with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers) to achieve targeting or tracing functions.
PEG chain: Serving as a hydrophilic spacer arm, it forms a hydration layer on the particle surface, reducing non-specific adsorption and immune system clearance, thus prolonging the carrier's circulation time in vivo.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
-
Masse moléculaire 2000 (Average)
-
SMILES
O=C(OCCOCC(COCCOC(CCN1C(C=CC1=O)=O)=O)(CC)COCCOC(CCN2C(C=CC2=O)=O)=O)CCN3C(C=CC3=O)=O.[n].[n].[n]
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)