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Cat. No.: HY-W1049002A

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3-Arm PEG5000-Mal

3-Arm PEG5000-Mal is a three-armed PEG derivative. The core structure of 3-Arm PEG5000-Mal consists of three PEG chains, each terminal of which is modified with a maleimide (Mal) group. The maleimide group in 3-Arm PEG5000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.

For research use only. We do not sell to patients.

Molecular Weight:5000 (Average)

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

3-Arm PEG5000-Mal Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
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Bioz

Biological Activity

Description

In Vitro

The structure of PEG-Alkyne comprises two key components that work synergistically:
Maleimide: Located at the end of the PEG chain, it acts as a reaction interface, enabling specific Michael addition reactions with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers) to achieve targeting or tracing functions.
PEG chain: Serving as a hydrophilic spacer arm, it forms a hydration layer on the particle surface, reducing non-specific adsorption and immune system clearance, thus prolonging the carrier's circulation time in vivo.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Chemical Information

Molecular Weight 5000 (Average)
SMILES

O=C(OCCOCC(COCCOC(CCN1C(C=CC1=O)=O)=O)(CC)COCCOC(CCN2C(C=CC2=O)=O)=O)CCN3C(C=CC3=O)=O.[n].[n].[n]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.