3-Arm PEG40000-Mal
3-Arm PEG40000-Mal is a three-armed PEG derivative. The core structure of 3-Arm PEG40000-Mal consists of three PEG chains, each terminal of which is modified with a maleimide (Mal) group. The maleimide group in 3-Arm PEG40000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
For research use only. We do not sell to patients.
- Molecular Weight:40000 (Average)
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
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Help & FAQs
Biological Activity
The structure of PEG-Alkyne comprises two key components that work synergistically:
Maleimide: Located at the end of the PEG chain, it acts as a reaction interface, enabling specific Michael addition reactions with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers) to achieve targeting or tracing functions.
PEG chain: Serving as a hydrophilic spacer arm, it forms a hydration layer on the particle surface, reducing non-specific adsorption and immune system clearance, thus prolonging the carrier's circulation time in vivo.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 40000 (Average)
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SMILES
O=C(OCCOCC(COCCOC(CCN1C(C=CC1=O)=O)=O)(CC)COCCOC(CCN2C(C=CC2=O)=O)=O)CCN3C(C=CC3=O)=O.[n].[n].[n]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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