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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2543 Results for "
class
" in MedChemExpress (MCE) Product Catalog:
Products (2543)
2543 Results for "class" in MCE Product Catalog:
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Research Areas:
Cephalothin (Cephalotin) sodium (Standard) is the analytical standard of Cephalothin sodium (HY-B1275). This product is intended for research and analytical applications. Cephalothin sodium is a semi-synthetic cephalosporin antibiotic and beta-lactam antibiotic. Cephalothin inhibits class C β-lactamase AmpC, with an Ki of 0.32 µM. Cephalothin sodium binds to penicillin-binding proteins, interfering with the cross-linking of peptidoglycan in the cell wall and thus hindering the normal synthesis of the bacterial cell wall. Cephalothin sodium shows antibacterial activity against a variety of bacteria. Cephalothin sodium can be used in hematological and nephrotoxicity studies .
Cat. No.: HY-N2362S
CAS No.: 102029-81-2
Synonyms: DL-2-Aminopropionic acid-13C-1
Cat. No.: HY-N2362S1
CAS No.: 131157-42-1
Synonyms: DL-2-Aminopropionic acid-13C-3
Cat. No.: HY-P10352
CAS No.: 111745-56-3
Cat. No.: HY-P10525
CAS No.: 167278-49-1
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Cat. No.: HY-W711035
CAS No.: 137641-05-5
Synonyms: AC 900001
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Picolinafen is a pyridine-class herbicide that acts as a phytoene desaturase (PDS) inhibitor. Picolinafen effectively controls broadleaf weeds and disrupts carotenoid biosynthesis. Picolinafen exhibits cytotoxicity to porcine trophectoderm (pTr) and luminal epithelial (pLE) cells. Picolinafen induces (ROS accumulation, calcium depletion, and activates (MAPK and PI3K signaling pathways, leading to decreased cell viability, increased apoptosis, impaired migration, and altered expression of implantation-related genes. Picolinafen has an LD50 value of 2.7 mg/kg in mammals and 7 μg/L in fish. Picolinafen exhibits toxic effects during zebrafish embryogenesis [1][2].
Cat. No.: HY-W715850
Synonyms: Ethyl 3-oxohexanoate-d5
Cat. No.: HY-W754400
Synonyms: 1,6-Anhydro-β-D-mannopyranose-13C6
Cat. No.: HY-Y0320GL
CAS No.: 67-68-5
Synonyms: DMSO (GMP Like)
Cat. No.: HY-L151
544 compounds
PROTACs (Proteolysis-targeting chimeras) is a class of molecules that utilize ubiquitin-proteasome system (UPS) to ubiquitinate and degrade target proteins. The PROTACs molecule consists of two ligands joined by a linker. The one-to-one interaction between PROTACs and target proteins determines the high efficiency of PROTACs, making it a potential molecule for targeted protein degradation (TPD) therapy.
MCE supplies a unique collection of 544 PROTACs that effectively degrade target proteins with more powerful screening capability. MCE PROTAC Library is a useful tool for signal pathway research, protein degradation therapy research, drug discovery and drug repurposing, etc.
Cat. No.: HY-182693
CAS No.: 2019223-60-8
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CPL302-253 is a PI3Kδ inhibitor with an IC50 of 12.20 nM and a human Kd of 0.85 nM. CPL302-253 functionally regulates PI3Kδ activity, blocks the production of IFNγ, IL-33 and ROS in immune cells, and affects immune function. CPL302-253 blocks the progression of asthma-inducing inflammatory responses in a mouse model of asthma. CPL302-253 can be used for research related to asthma .
Cat. No.: HY-18740
CAS No.: 79855-88-2
Synonyms: HL 725 free base
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Trequinsin (HL 725 free base) is a PDE inhibitor, CatSper channel activator, and sperm potassium channel modulator. Trequinsin targets PDE3 with an IC50 of <1 nM. Trequinsin enhances currents and elevates intracellular calcium and cGMP levels via direct activation of the CatSper channel, while inhibiting the outward current conductance of sperm potassium channels. Without inducing premature acrosome reaction, Trequinsin significantly enhances sperm hyperactivated motility, forward motility, and the ability to penetrate viscous media. Trequinsin exerts age-specific positive inotropic and positive lusitropic effects on rabbit ventricular papillary muscles. Trequinsin has been used in studies on the mechanisms underlying male infertility (e.g., asthenozoospermia) .
Cat. No.: HY-P1924
CAS No.: 1977546-93-2
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Cat. No.: HY-P1924A
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Cat. No.: HY-P82565
Synonyms: SORL1; C11orf32; Sortilin-related receptor; Low-density lipoprotein receptor relative with 11 ligand-binding repeats; LDLR relative with 11 ligand-binding repeats; LR11; SorLA-1; Sorting protein-related receptor containing LDLR class A repe
Cat. No.: HY-P85374
Synonyms: SORL1; C11orf32; Sortilin-related receptor; Low-density lipoprotein receptor relative with 11 ligand-binding repeats; LDLR relative with 11 ligand-binding repeats; LR11; SorLA-1; Sorting protein-related receptor containing LDLR class A repe
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
