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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3831 Results for "
System
" in MedChemExpress (MCE) Product Catalog:
Products (3831)
3831 Results for "System" in MCE Product Catalog:
Cat. No.: HY-187006
CAS No.: 1110983-52-2
Research Areas:
Nampt-IN-21 is a NAMPT inhibitor. Nampt-IN-21 serves as a Ligand for Target Protein for PROTAC for the synthesis of PROTAC NAMPT degraders, such as PROTAC NAMPT Degrader-30 (HY-152154). Nampt-IN-21 is applicable to the research of ovarian cancer .
Cat. No.: HY-187391
CAS No.: 3033385-55-3
Target:
Research Areas:
RIPK1-ligand-4 is a RIMTAC E3 recruiting ligand that indirectly recruits VHL E3 ligases by binding to RIPK1 and hijacking the endogenous RIPK1-VHL complex. RIPK1-ligand-4 can be used to synthesize the BRD4 RIMTAC-1 (HY-187390) PROTAC degrader .
Target:
Cat. No.: HY-P992162
Research Areas:
Cat. No.: HY-W019151
CAS No.: 569-31-3
Category:
Natural Products Metabolic Disease Plants Papaver somniferum Linn. Endogenous metabolite Disease Research Fields Papaveraceae
Target:
Cat. No.: HY-W019151R
CAS No.: 569-31-3
Target:
Cat. No.: HY-W019151S
CAS No.: 29809-15-2
Cat. No.: HY-W1137162
CAS No.: 3107976-26-8
Target:
Research Areas:
CRBN ligand-904 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), which is used to recruit cereblon protein. CRBN ligand-904 can be linked to a target protein ligand via a linker to form a PROTAC, such as PROTAC GSK3 degrader-1 (HY-185634) .
Cat. No.: HY-W140488
CAS No.: 253685-27-7
Synonyms: 10:0 PE
1,2-Didecanoyl-sn-glycero-3-phosphoethanolamine, a phospholipid, showes very promising P-gp inhibitory results at a concentration of 0.3 mM.
Cat. No.: HY-W250112
CAS No.: 8068-05-1
Cat. No.: HY-W340832
CAS No.: 384835-51-2
18:1 Biotinyl Cap PE is a fluorescent lipid, which features a head group that has been altered to include biotinyl cap PE.
Cat. No.: HY-W343736
CAS No.: 67303-93-9
Synonyms: 1,3-DPPE; 1,3-Dipalmitoyl-sn-glycero-2-PE
1,3-Dipalmitoyl-glycero-2-phosphoethanolamine is a phospholipid containing the saturated long-chain (16:0) stearic acid inserted at the sn-1 and sn-3 positions and PE at the sn-2 site. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
Cat. No.: HY-W440690
Cholesterol-PEG2000-amine is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles.
Cat. No.: HY-W440698
Cholesterol-PEG2000-Acid is a polydisperse PEG derivative which can be used to create liposome as drug carrier for delivering therapeutic agents into tissues.
Cat. No.: HY-W440706
Cholesterol-PEG2000-alcohol is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. The amine can react with an activated NHS ester to form a stable amide bond.
Cat. No.: HY-W440711
Cholesterol-PEG-Biotin (MW 2000) is a pegylated lipids which has strong binding to avidin or streptavidin.
Cat. No.: HY-W440719
Cholesterol-PEG2000-MAL is a PEG derivative and can be used to prepare liposome or nanoparticle due to its ability to self-assemble in water. The maleimide moiety is reactive with thiol molecule to form a covalent thioether bond.
Cat. No.: HY-W440727
Cholesterol-PEG2000-Vinylsulfone is a thiol reactive polyPEG via thiol-ene reaction to form a thioether bond. It can self-assemble in water and is used to prepare liposome as drug vehicle for targeted delivery into tissues.
Cat. No.: HY-W440820
CAS No.: 692250-70-7
Bis(bis(2-carboxyethyl)aminopropyl)methylamine is a symmetrical branched linker featuring three tertiary amines and four carboxylic acids. Each carboxylic acid is open to forming esters or amides. It can be used in developing lipid nanoparticles.
Cat. No.: HY-W440957
CAS No.: 69441-09-4
Synonyms: PC(16:0/14:0); 1-palmitoyl-2-myristoyl-sn-glycero-3-phosphocholine
PMPC is a phosphatidylcholine with asymmetrical fatty acid. Palmitic acid occupies sn-1 position while myristic acid is placed at the sn-2 position.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
