3033385-55-3
3033385-55-3
Chemical Structure
RIPK1-ligand-4
- CAS. Nr.: 3033385-55-3
- Formula:C22H15F4N3O2S
- Molecular Weight:461.43
InChIKey: UZXVXUJCEYTXDB-UHFFFAOYSA-N
SMILES: NC1=NC2=CC=C(C3=CC(NC(CC4=CC=CC(OC(F)(F)F)=C4)=O)=C(C=C3)F)C=C2S1
Biological Activity: RIPK1-ligand-4 is a RIMTAC E3 recruiting ligand that indirectly recruits VHL E3 ligases by binding to RIPK1 and hijacking the endogenous RIPK1-VHL complex. RIPK1-ligand-4 can be used to synthesize the BRD4 RIMTAC-1 (HY-187390) PROTAC degrader[1].
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RIPK1-ligand-4 | RIPK1-ligand-4 is a RIMTAC E3 recruiting ligand that indirectly recruits VHL E3 ligases by binding to RIPK1 and hijacking the endogenous RIPK1-VHL complex. RIPK1-ligand-4 can be used to synthesize the BRD4 RIMTAC-1 (HY-187390) PROTAC degrader. | |||||||||||||||||||||
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References
Keywords
