148 Results for "

CD40

" in MedChemExpress (MCE) Product Catalog:
Products (148)

148 Results for "CD40" in MCE Product Catalog:

Cat. No.: HY-P99821
CAS No.: 2050816-56-1
Synonyms: ABBV-323

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Ravagalimab (ABBV-323) is a CD40 antagonist (EC50: 3.7 nM). Ravagalimab can be used for research of Crohn's disease .
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Cat. No.: HY-P99572
CAS No.: 2253891-70-0
Synonyms: BNT-312; DuoBody-CD40x-4-1BB; GEN1042

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology Cancer

Tecaginlimab (BNT-312) is a Fc-inert bispecific antibody for dual targeting and conditional stimulation of CD40 and 4-1BB. Tecaginlimab can enhance priming and reactivation of tumor-specific immunity .
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Cat. No.: HY-P99321
CAS No.: 299423-37-3
Synonyms: BMS 224819; Chi220; Anti-Human CD40 Recombinant Antibody

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology Cancer

Teneliximab (BMS-224819) is a chimeric monoclonal antibody, blocks the CD40-CD40L interaction. Teneliximab (BMS-224819) has partial agonist activity resulting in some signaling through CD40 and peripheral B cell depletion .
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Cat. No.: HY-P99046
CAS No.: 1622140-49-1
Synonyms: CP-870893; RG-7876

Target:  

TNF Receptor

Research Areas:  

Cancer

Selicrelumab is an agonist CD40 antibody, induces changes in the tumor microenvironment. Selicrelumab can be used for the research of pancreatic cance and neoadjuvant study .
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Cat. No.: HY-P99167
CAS No.: 903512-50-5
Synonyms: HCD122

Target:  

TNF Receptor

Research Areas:  

Cancer

Lucatumumab (HCD122) is a fully human anti-CD40 antagonist monoclonal antibody, which blocks CD40/CD40L-mediated signaling. Lucatumumab efficiently mediates antibody-dependent cell-mediated cytotoxicity (ADCC) and clearance of tumor cells, can be used for refractory lymphomas, CLL and multiple myeloma research .
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Cat. No.: HY-P99603
CAS No.: 1629760-27-5
Synonyms: SEA-CD40

Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

Cifurtilimab (SEA-CD40) is an agonistic nonfucosylated, human IgG1 monoclonal antibody directed against CD40. Cifurtilimab shows antitumor activities .
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Cat. No.: HY-P99257
CAS No.: 1453067-91-8
Synonyms: ASKP 1240

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Bleselumab (ASKP 1240) is a human anti-CD40 monoclonal antibody (mAb). Bleselumab binds to human CD40 with high affinity (Kd: 0.24 nM). Bleselumab inhibits immune responses by blocking the interaction of CD40 with its ligand CD40L. Bleselumab prevents organ transplant rejection .
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Cat. No.: HY-122663
CAS No.: 402564-79-8
Purity:  99.81%
Target:  

TNF Receptor

Research Areas:  

Cancer

(Rac)-BIO8898 is a CD40-CD154 co-stimulatory interaction inhibitor. (Rac)-BIO8898 inhibits CD154 binding to CD40-Ig with an IC50 of 25 μM .
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Cat. No.: HY-P990111

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

BMS-986325 (anti-CD40) is a CD40 inhibitor, and can be used for primary Sj gren's syndrome research .
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Cat. No.: HY-154822
CAS No.: 2101765-83-5
Purity:  98.67%
Target:  

TNF Receptor NF-κB

Research Areas:  

Inflammation/Immunology

DRI-C25441 is a potent blocker of CD40 and CD40L interaction, with an IC50 of 0.36 μM. DRI-C25441 can inhibit the immune response induced by alloantigen. can inhibit CD40L induced activation of NF-κB signaling pathway. DRI-C25441 commonly is used in research on immune conditions .
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Cat. No.: HY-P990860

Target:  

TNF Receptor

Research Areas:  

Cancer

Anti-CD40 Antibody (G28.5) is a kind of mouse IgG1 κ chimeric agonistic antibody, targeting to human CD40. Anti-CD40 Antibody (G28.5) can activate CD40 signaling and promote anti-tumor T cell responses. Anti-CD40 Antibody (G28.5) can be used for the research of cancer, such as endometrial cancer .
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Cat. No.: HY-154821A
Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

DRI-C21041 DIEA is a CD40/CD40L interaction inhibitor, with an IC50 of 0.31 μM. DRI-C21041 DIEA inhibits the immune response induced by alloantigen .
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Cat. No.: HY-125025
CAS No.: 433234-16-3
Target:  

TNF Receptor

SMI 6860766, a small molecule inhibitor of CD40-TRAF6 interaction, improves glucose tolerance, reduces immune cell accumulation in adipose tissue, and reduces AT inflammation .
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Cat. No.: HY-P10399
CAS No.: 1690215-31-6
Synonyms: Mouse KGYY15; KGYY15 peptide
Target:  

TNF Receptor

Research Areas:  

Metabolic Disease

KGYY15 (Mouse KGYY15) is a CD40 targeting peptide, which weakly inhibits the CD40-CD40L interaction with IC50 of more than 1mM. KGYY15 activates 33% NF-κB pathway at 100 μM .
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Cat. No.: HY-154821
CAS No.: 2101765-78-8
Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

DRI-C21041 is a CD40/CD40L interaction inhibitor, with an IC50 of 0.31 μM. DRI-C21041 inhibits the immune response induced by alloantigen .
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Cat. No.: HY-P990269

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology Cancer

Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1) is a mouse-derived IgG2a κ type antibody inhibitor, targeting to mouse CD40L/CD154. Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1) is a chimeric version of the original MR-1 antibody (HY-P990134). The variable domain sequences are identical to the original MR-1 but the constant region sequences have been switched from Armenian hamster IgG to mouse IgG2a. Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1) contains a LALA-PG mutation in the Fc fragment rendering it unable to bind to endogenous Fcγ receptors. Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1) blocks CD40/CD40L signaling. Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1) can be used for researches of cancer, inflammation and immunology.
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Cat. No.: HY-174738
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human CD40 mRNA encodes the human CD40 molecule (CD40) protein, a member of the TNF-receptor superfamily. CD40 is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.
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Cat. No.: HY-RS02246
Research Areas:  

Others

CD40 Human Pre-designed siRNA Set A contains three designed siRNAs for CD40 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS16527
Research Areas:  

Others

Cd40 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cd40 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS22958
Research Areas:  

Others

Cd40 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cd40 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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