93 Results for "

Npy

" in MedChemExpress (MCE) Product Catalog:
Products (93)

93 Results for "Npy" in MCE Product Catalog:

Cat. No.: HY-P4123
CAS No.: 1231898-26-2
Target:  

MMP

TAT (47-57) GGG-Cys (Npys) is a cell-penetrating peptide and delivery carrier derived from TAT. TAT (47-57) GGG-Cys (Npys) facilitates the translocation of conjugated drug molecules across cell membranes. TAT (47-57) GGG-Cys (Npys) acts as a delivery carrier for MT1-MMP inhibitors. TAT (47-57) GGG-Cys (Npys) is applicable to research on diseases associated with MT1-MMP activity, such as cancer, arthritis, heart disease, and vascular disorders .
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Cat. No.: HY-P1011
CAS No.: 113662-54-7
Synonyms: Npy 13-36
Research Areas:  

Neurological Disease

Neuropeptide Y (13-36), porcine is a selective neuropeptide Y2 receptor agonist .
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Cat. No.: HY-P11291A
Research Areas:  

Metabolic Disease

NNC0165-1273 TFA is a selective NPY Y2 receptor agonist with a Ki of 2 nM and an EC50 of 5.0 nM. NNC0165-1273 TFA blocks Ghrelin-induced cFos expression. NNC0165-1273 TFA reduces nocturnal food intake, attenuates feeding behavior, induces early satiety, and causes dose-dependent decreases in body weight and fat mass in diet-induced obese mice. When used in combination with Semaglutide (HY-114118), NNC0165-1273 TFA reduces preference for high-fat diet, promotes body weight loss, and produces sustained weight loss effects in diet-induced obese rats. NNC0165-1273 TFA can be used in studies related to diet-induced obesity .
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Cat. No.: HY-P1322
CAS No.: 153549-84-9
Research Areas:  

Neurological Disease

[D-Trp34]-Neuropeptide Y is a potent and selective neuropeptide Y (NPY) Y5 receptor agonist. [D-Trp34]-Neuropeptide Y is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6 receptors. [D-Trp34]-Neuropeptide Y markedly increases food intake in rats .
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Cat. No.: HY-107565
CAS No.: 3343-39-3
Purity:  99.86%
Target:  

Histamine Receptor

Research Areas:  

Inflammation/Immunology

2-Pyridylethylamine is a histamine-1 (H1R) receptor agonist. 2-Pyridylethylamine can reduce the joint injury induced by formalin in rats. 2-Pyridylethylamine can be used to study the spinal cord release of neuropeptide (NPY) .
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Cat. No.: HY-P1845A
Research Areas:  

Neurological Disease

PACAP-38 (31-38), human, mouse, rat TFA is a fragment containing the C-terminal 31-38 fragment of PACAP (1-38), human, ovine, rat (HY-P0221). PACAP-38 (31-38), human, mouse, rat TFA does not bind to the PACAP receptor .
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Cat. No.: HY-156922
CAS No.: 432506-24-6
Purity:  99.86%
NPY-5 receptor antagonist-1 (Example 57) is a NPY-5 receptor antagonist (Ki: < 1 μM). NPY-5 receptor antagonist-1 can be used for research of obesity, feeding disorders, as well as other neurological diseases .
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Cat. No.: HY-RS09510
Research Areas:  

Others

NPY Human Pre-designed siRNA Set A contains three designed siRNAs for NPY gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P4087B
Target:  

HIV

Research Areas:  

Others

Cys(Npys)-(Arg)9 acetate is a synthetic cationic cell-penetrating peptide with a reversible thiol-reactive nitropyridyl (Npys) group. Cys(Npys)-(Arg)9 acetate efficiently mediates the internalization and delivery of various "cargo" such as proteins and antibodies by forming reversible disulfide bonds with surface-exposed cysteine residues. Cys(Npys)-(Arg)9 acetate endows TALEN proteins with cell-penetrating activity, enabling gene knockout in mammalian cells and protein transduction in wheat microspores. Cys(Npys)-(Arg)9 acetate can be conjugated with antibodies to form cationized IgG for enhancing endosomal escape of oligonucleotides, or form siRNA delivery complexes. When the molar ratio of Cys(Npys)-(Arg)9 acetate to loaded molecules is higher than 1:1, it exerts certain cytotoxic effects on cells. Cys(Npys)-(Arg)9 acetate can be used in studies related to oral squamous cell carcinoma and HIV infection .
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Cat. No.: HY-P1324
CAS No.: 313988-89-5
Research Areas:  

Neurological Disease

[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide is a potent and selective neuropeptide Y Y5 receptor agonist with an IC50 of 0.24 nM for binding to the hY5 receptor. [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide induces a high amount of food intake .
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Cat. No.: HY-P4137
CAS No.: 220337-24-6
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Cys(Npys) Antennapedia Peptide, amide is a peptide. Cys(Npys) Antennapedia Peptide, amide can be used for various biochemical studies .
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Cat. No.: HY-148179
CAS No.: 322723-35-3
Purity:  ≥98.0%
Research Areas:  

Neurological Disease

Neuropeptide Y5 receptor ligand-1 (compound 54), a carbazole derivative, is a potent neuropeptide Y5 (NPY-5) receptor antagonist .
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Cat. No.: HY-W141779
CAS No.: 76880-29-0
Research Areas:  

Others

Boc-Cys(Npys)-OH is a cysteine derivative .
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Cat. No.: HY-P4099A
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Cys(Npys)-(D-Arg)9 TFA is an amphipathic R9 cell penetrating peptide (CPP). Cys(Npys)-(D-Arg)9 TFA has cytotoxicity for microspore cells with the amount higher than 1 nmol .
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Cat. No.: HY-P4101
Target:  

HIV

Research Areas:  

Infection

Cys(Npys)-TAT (47-57) is a peptide fragment of TAT peptide and it is able to interact with plasmid DNA electrostatically. Cys(Npys)-TAT (47-57) is corresponding to the transduction domain of TAT with an activated cysteine residue C. TAT is a small nuclear transcriptional activator protein encoded by HIV-1 .
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Cat. No.: HY-P3678
CAS No.: 114495-97-5
Neuropeptide Y (18-36) (porcine) is a competitive neuropeptide Y (NPY) cardiac receptor antagonist. Neuropeptide Y (18-36) (porcine) inhibits the binding of I-NPY to cardiac ventricular membranes in a concentration-dependent manner with an IC50 value of 158 nM and an Ki value of 140 nM. Neuropeptide Y (18-36) (porcine) can be used for the research of congestive heart failure .
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Cat. No.: HY-P4060A
Research Areas:  

Others

Pancreatic polypeptide TFA is a neuropeptide Y (NPY) Y4/Y5 receptor agonist.
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Cat. No.: HY-P5757
CAS No.: 153549-78-1
Synonyms: (D-Trp32)-Npy
Research Areas:  

Neurological Disease

(D-Trp32)-Neuropeptide Y (porcine) is a highly selective neuropeptide Y (NPY) Y5 receptor agonist. (D-Trp32)-Neuropeptide Y (porcine) has orexigenic activity and inhibits Forskolin (HY-15371)-stimulated cAMP formation .
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Cat. No.: HY-120096
CAS No.: 191868-13-0
Research Areas:  

Neurological Disease

BIBO3304 free base is a nonpeptide neuropeptide Y Y1 receptor antagonist. BIBO3304 free base displays subnanomolar affinity for both the human and the rat Y1 receptor, with IC50 values of 0.38 nM and 0.72 nM, respectively. BIBO3304 free base significantly inhibits food intake induced by application of NPY or by fasting .
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Cat. No.: HY-P4099
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Cys(Npys)-(D-Arg)9 is an amphipathic R9 cell penetrating peptide (CPP). Cys(Npys)-(D-Arg)9 has cytotoxicity for microspore cells with the amount higher than 1 nmol .
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