130 Results for "

Sphingolipids

" in MedChemExpress (MCE) Product Catalog:
Products (130)

130 Results for "Sphingolipids" in MCE Product Catalog:

Cat. No.: HY-P2982
CAS No.: 128543-23-7
Target:  

Liposome

Research Areas:  

Metabolic Disease

Ceramide 1-phosphate is a bioactive lipid and one of the key components of sphingolipids. Ceramide 1-phosphate playing diverse roles in cellular behaviors such as cell differentiation, migration, proliferation and death .
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Cat. No.: HY-154921
CAS No.: 4682-48-8
Purity:  ≥98.0%
Synonyms: LacCer (bovine buttermilk)
Research Areas:  

Inflammation/Immunology

Lactosylceramide (bovine buttermilk) (LacCer (bovine buttermilk)) is a sphingolipid that highly expressed on the plasma membranes of human phagocytes. Lactosylceramide mediates phagocytosis, chemotaxis, and superoxide generation .
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Cat. No.: HY-165136
CAS No.: 475662-40-9
Synonyms: SMs (buttermilk)
Target:  

Endogenous Metabolite

Research Areas:  

Others

Sphingomyelins, milk (SMs (buttermilk)) are compounds studied in sphingolipids, which play important roles in various biological processes.
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Cat. No.: HY-138875
CAS No.: 13018-48-9
Purity:  99.90%
Tetraacetylphytosphingosine is a sphingolipid metabolite produced by phytosphingosine acetylation. Tetraacetylphytosphingosine exerts its inhibitory action on angiogenesis through the inhibition of MAPK activation and intracellular calcium increase . Tetraacetylphytosphingosine induces apoptosis in HaCaT cells .
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Cat. No.: HY-N10706A
CAS No.: 35299-94-6
Target:  

Endogenous Metabolite

Research Areas:  

Cardiovascular Disease

3-Keto sphinganine (d18:0) hydrochloride serves as the substrate for 3-keto-dihydrosphingosine reductase in the de novo sphingolipid synthesis pathway, and is a key intermediate in the de novo synthesis of sphingoid long-chain bases. 3-Keto sphinganine (d18:0) hydrochloride can be used in studies related to thrombocytopenia, anemia .
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Cat. No.: HY-165677
CAS No.: 74645-25-3
Target:  

Endogenous Metabolite

Research Areas:  

Neurological Disease

C22 Galactosylceramide is a sphingolipid present in the central nervous system, exhibiting elevated levels in the spinal cord of mice on a methionine-restricted diet, while not affecting the brain or liver; furthermore, it has been identified in the postmortem hippocampus of Alzheimer's disease patients.
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Cat. No.: HY-N3570
CAS No.: 88642-46-0
Cerebroside B, a sphingolipid compound, is a non-racespecific elicitor, which elicits defense responses in rice .
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Cat. No.: HY-118442
CAS No.: 24558-60-9
Synonyms: Tetradecasphing-4-enine
Sphingosine (d14:1) (Tetradecasphing-4-enine), a sphingolipid, is a potent Protein kinase C (PKC) inhibitor. Sphingosine (d14:1) prevents its interaction with sn-1,2-diacylglycerol (DAG)/Phorbol esters .
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Cat. No.: HY-116017
CAS No.: 111122-57-7
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

C10 ceramide is an endogenous, bioactive sphingolipid,
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Cat. No.: HY-N15930
CAS No.: 1196670-47-9
Category:  

Lipids

16:0 propargyl SM (d18:1-16:0) is a clickable sphingolipid.
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Cat. No.: HY-139261
CAS No.: 2190487-94-4
Purity:  ≥99.0%
Synonyms: 1-Deoxyso; 14Z-1-Deoxysphingosine (d18:1)
Research Areas:  

Metabolic Disease

1-Deoxysphingosine (m18:1(14Z)) (1-Deoxyso; 14Z-1-Deoxysphingosine (d18:1)) is an ester product.
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Cat. No.: HY-165062
CAS No.: 54336-69-5
Synonyms: Stearoyl sphingomyelin; Sphingomyelin (d18:1/18:0); N-Octadecanoyl sphingosylphosphorylcholine
Target:  

Others

Research Areas:  

Metabolic Disease

C18 Sphingomyelin (d18:1/18:0) is a form of sphingomyelin and can be used for study of sphingolipid metabolites .
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Cat. No.: HY-148388
CAS No.: 58909-84-5
Purity:  98.60%
Synonyms: N-Stearoyl-D-sphingomyelin
Target:  

Phospholipase

Research Areas:  

Cancer

N-Stearoylsphingomyelin (N-Stearoyl-D-sphingomyelin) is a sphingolipid, which can inhibit Phospholipase Cδ1 (PLCδ1) .
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Cat. No.: HY-115708
CAS No.: 164576-03-8
Synonyms: Cer(t18:0/22:0); Ceramide (t18:0/22:0); C22 Phytosphingosine (t18:0/22:0)
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

C22 Phytoceramide is a sphingolipid that has been found in Moro blood orange (C. sinensis) peels. It has also been found in primary human astrocytes.
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Cat. No.: HY-139286
CAS No.: 1823021-14-2
Synonyms: Pacsph; Pacsphingosine (d18:1)
Research Areas:  

Others

Photoclick sphingosine (Pacsph) is a photosensitizing and clickable sphingosine analog. Photoclick sphingosine is metabolized in cells into endogenous lipid metabolic pathways and can be visualized by its clickable alkyne group. Photoclick sphingosine can be used to study intracellular sphingolipid metabolism and subcellular localization .
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Cat. No.: HY-N6723S
CAS No.: 1217481-36-1
Fumonisin B2- 13C34 is the 13C labeled Fumonisin B2 (HY-N6723) . Fumonisin B2, a mycotoxin produced by Fusarium moniliforme in various grains, is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis .
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Cat. No.: HY-N6719S
CAS No.: 1217458-62-2
Fumonisin B1- 13C34 is the 13C labeled Fumonisin B1 (HY-N6719) . Fumonisin B1 is a mycotoxin produced from Fusarium moniliforme. Fumonisin B1 is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis. Fumonisin B1 is the most abundant and toxic fumonisin .
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Cat. No.: HY-165034
CAS No.: 34249-41-7
Synonyms: ((±)-2'-Hydroxy) cer(d18:1/18:0); 18:0 (2R/S-OH)-Ceramide; ((±)-2'-Hydroxy) ceramide (d18:1/18:0)
Target:  

Endogenous Metabolite

Research Areas:  

Others

C18 ((±)-2'-Hydroxy) ceramide ((±)-2'-Hydroxy) cer) (d18:1/18:0) is a bioactive sphingolipid found in the stratum corneum layer of mammalian epidermis. Ceramides maintains the normal hydration levels required for the normal physiological .
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Cat. No.: HY-156207
CAS No.: 261155-87-7
Synonyms: AdaGb3; Adamantyl Gb3; C2 Adamantanyl Ceramide Trihexoside (d18:1/2:0)
Target:  

P-glycoprotein

Research Areas:  

Cancer

C2 Adamantanyl globotriaosylceramide (d18:1/2:0) (AdaGb3), a water-soluble globotriaosylceramide analog, is a bioactive sphingolipid. C2 Adamantanyl globotriaosylceramide (d18:1/2:0) reverses MDR1-MDCK cell drug resistance. C2 Adamantanyl globotriaosylceramide (d18:1/2:0) has high affinity for verotoxin (VT) .
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Cat. No.: HY-113934
CAS No.: 105615-55-2
Purity:  ≥98.0%
Synonyms: L-threo-Sphingosylphosphorylcholine
Target:  

LPL Receptor

Research Areas:  

Cancer

L-threo Lysosphingomyelin (d18:1) (L-threo-Sphingosylphosphorylcholine) is an endogenous bioactive sphingolipid. L-threo Lysosphingomyelin (d18:1) is a potent S1P receptor agonist with EC50s of 19.3, 131.8, and 313.3 nM for hS1P1, hS1P3, and hS1P2, respectively .
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