13018-48-9
13018-48-9
Chemical Structure
Tetraacetylphytosphingosine
- CAS No.: 13018-48-9
- Formula:C26H47NO7
- Molecular Weight:485.65
IUPAC Name: (2S,3S,4R)-2-acetamidooctadecane-1,3,4-triyl triacetate
InChIKey: SGTYQWGEVAMVKB-NXCFDTQHSA-N
SMILES: CCCCCCCCCCCCCC[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H](NC(C)=O)COC(C)=O
Biological Activity: Tetraacetylphytosphingosine is a sphingolipid metabolite produced by phytosphingosine acetylation. Tetraacetylphytosphingosine exerts its inhibitory action on angiogenesis through the inhibition of MAPK activation and intracellular calcium increase[1]. Tetraacetylphytosphingosine induces apoptosis in HaCaT cells[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Tetraacetylphytosphingosine | 99.90% | Tetraacetylphytosphingosine is a sphingolipid metabolite produced by phytosphingosine acetylation. Tetraacetylphytosphingosine exerts its inhibitory action on angiogenesis through the inhibition of MAPK activation and intracellular calcium increase. Tetraacetylphytosphingosine induces apoptosis in HaCaT cells. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.68
HY-N71572-2'-(Hydroxytetracosanoylamino)-octadecane-1,3,4-triol tetraacetate -
Similarity Score 0.64
HY-164263N-Acetylphytosphingosine -
Similarity Score 0.62
HY-19602Cedefingol -
Similarity Score 0.62
HY-W590664C2 Dihydroceramide -
Similarity Score 0.60
HY-W590572N-Butyroyl Phytosphingosine -
Similarity Score 0.59
HY-145517C6-Phytoceramide -
Similarity Score 0.58
HY-145518C8 Phytoceramide (t18:0/8:0) -
Similarity Score 0.58
HY-165070SABRAC -
Similarity Score 0.58
HY-W590665C4 Dihydroceramide -
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References
- [1]. Yoo Bin Kwon, et al. Anti-angiogenic effect of tetraacetyl-phytosphingosine. Exp Dermatol. 2007 Apr;16(4):311-7. [Content Brief]
- [2]. H J Kim, et al. Potentiation of UVB-induced apoptosis by novel phytosphingosine derivative, tetraacetyl phytosphingosine in HaCaT cell and mouse skin. Apoptosis. 2004 Jul;9(4):449-56. [Content Brief]
