116 Results for "

UTP

" in MedChemExpress (MCE) Product Catalog:
Products (116)

116 Results for "UTP" in MCE Product Catalog:

Cat. No.: HY-135780A
Purity:  99.69%
Synonyms: 3'-dUTP trisodium
3'-Deoxyuridine-5'-triphosphate trisodium (3'-dUTP trisodium) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate trisodium strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM .
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Cat. No.: HY-141567
CAS No.: 1175-34-4
Synonyms: Pseudo-UTP
Pseudouridine 5'-triphosphate (Pseudo-UTP) is a modified ribonucleoside triphosphate and uracil base-modified UTP derivative. Pseudouridine 5'-triphosphate enhances translational properties and stability of mRNA, reduces innate immune responses in mammalian cells, and inhibits signal-dependent transcription termination of vaccinia virus early gene transcription while supporting transcription elongation. Pseudouridine 5'-triphosphate can be used for the research of vaccinia virus infection .
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Cat. No.: HY-155878
CAS No.: 2710-64-7
Research Areas:  

Others

5-Fluoro-2′-deoxy-UTP can be used as a substrate for DNA synthesis .
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Cat. No.: HY-D1686B
Biotin-16-UTP tetrasodium is an active substrate for RNA polymerase. Biotin-16-UTP tetrasodium can replace UTP in the in vitro transcription reaction for RNA labeling .
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Cat. No.: HY-154840
CAS No.: 20188-72-1
Purity:  87.53%
Synonyms: 4-Thio-UTP tetralithium
Target:  

P2Y Receptor

Research Areas:  

Inflammation/Immunology

4-Thiouridine 5′-triphosphate (4-Thio-UTP) tetrasodium (Compound 15) is a UTP analog and potent P2Y2 and P2Y4 agonist with EC50 values of 35 and 350 nM for hP2Y2 and hP2Y4, respectively. 4-Thiouridine 5′-triphosphate tetrasodium can be used in cross-linking experiments and transcriptional complex labeling studies .
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Cat. No.: HY-E70028
CAS No.: 223918-15-8
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

UDP-sugar pyrophosphorylase (BlUSP) is the enzyme capable of activating glucose-1-phosphate (Glc-1-P) to UDP-glucose (UDP-Glc). UDP-sugar pyrophosphorylase (BlUSP) catalyzes a reversible transfer of the uridyl group from UTP to sugar-1-phosphate, producing UDP-sugar and pyrophosphate (PPi) .
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Cat. No.: HY-134178A
Synonyms: 5-Fluorouridine-5'-triphosphate trisodium
Research Areas:  

Metabolic Disease

5-F-UTP (5-Fluorouridine-5'-triphosphate) trisodium is a monomeric raw material that can be used for nucleic acid synthesis.
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Cat. No.: HY-174485
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

OVA mRNA (N1-Me-Pseudo UTP) is an mRNA encoding chicken ovalbumin. The substitution with N1-Me-Pseudo UTP (m1Ψ) improves protein expression and reduces innate immune response. OVA mRNA binds to the STING-activating polymer PD18 and is encapsulated in optimized lipid nanoparticles to construct an mRNA vaccine platform (PD18 LNP). This platform not only enhances the lymphatic delivery efficiency and protein expression of mRNA, but also potently adjuvates immune responses via activating the STING pathway .
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Cat. No.: HY-107372S2
Purity:  ≥98.0%
Synonyms: UTP-13C9 dilithium; Uridine 5'-triphosphate-13C9 dilithium
Uridine triphosphate- 13C9 (UTP- 13C9 dilithium; Uridine 5'-triphosphate- 13C9) dilithium is 13C-labeled Uridine triphosphate (HY-107372). Uridine triphosphate (UTP;Uridine 5'-triphosphate) is a nucleotide that regulates the functions of the pancreas in endocrine and exocrine secretion, proliferation, channels, transporters, and intracellular signaling under normal and disease states.
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Cat. No.: HY-E70025
Synonyms: GlcNAc1pUT
Target:  

Others

Research Areas:  

Others

N-acetylglucosamine-1-P uridyltransferase (AGX1) (EC 2.3.1.157) (GlcNAc1pUT) is a bifunctional acetyltransferase/uridyltransferase. N-acetylglucosamine-1-P uridyltransferase (AGX1) binds GlcNAc-1-P and UTP, and catalyzes an uridyltransfer reaction to synthesize UDP-GlcNAc. N-acetylglucosamine-1-P uridyltransferase (AGX1) is a bifunctional enzyme exclusive to prokaryotes .
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Cat. No.: HY-135780
CAS No.: 69199-40-2
Synonyms: 3'-dUTP
3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM .
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Cat. No.: HY-W013093R
CAS No.: 19817-92-6
Synonyms: UTP trisodium salt (Standard); Uridine 5'-triphosphate trisodium salt (Standard)
Uridine triphosphate (trisodium salt) (Standard) is the analytical standard of Uridine triphosphate (trisodium salt). This product is intended for research and analytical applications. Uridine triphosphate (UTP) trisodium salt is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate trisodium salt activates membrane-bound P2Y2 receptors .
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Cat. No.: HY-107372S
CAS No.: 285978-18-9
Synonyms: UTP-13C9,15N2 sodium; Uridine 5'-triphosphate-13C9,15N2 sodium
Uridine triphosphate- 13C9, 15N2 (UTP- 13C9, 15N2) sodium is a labeled Uridine triphosphate sodium. Uridine triphosphate sodium can be used in nucleic acid synthesis.
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Cat. No.: HY-N11522
CAS No.: 23198-01-8
Synonyms: 5-Methyl-UTP
5-Methyluridine 5′-triphosphate (5-Methyl-UTP) is a UTP (HY-107372) analog. 5-Methyluridine 5′-triphosphate stimulates incorporation of [ 3H]-GMP by RNA polymerase I much better than UTP .
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Cat. No.: HY-116307
CAS No.: 35763-29-2
Target:  

P2Y Receptor

Research Areas:  

Cardiovascular Disease

2-Thio-UTP is a selective P2Y2 inhibitor with an EC50 value of 50 nM. 2-Thio-UTP reduces pro-fibrotic gene expression and protein α-smooth muscle actin. 2-Thio-UTP has the potential for the research of calcific aortic valve stenosis (CAVS) .
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Cat. No.: HY-154840A
CAS No.: 68507-49-3
Synonyms: 4-Thio-UTP tetrasodium
Target:  

P2Y Receptor

Research Areas:  

Inflammation/Immunology

4-Thiouridine 5′-triphosphate (4-Thio-UTP) tetralithium (Compound 15) is a UTP analog and potent P2Y2 and P2Y4 agonist with EC50 values of 35 and 350 nM for hP2Y2 and hP2Y4, respectively. 4-Thiouridine 5′-triphosphate tetralithium can be used in cross-linking experiments and transcriptional complex labeling studies .
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Cat. No.: HY-108650
CAS No.: 1343364-70-4
Synonyms: 2-Thiouridine 5′-triphosphate tetrasodium
Target:  

P2Y Receptor

Research Areas:  

Cancer

2-Thio-UTP tetrasodium is a potent P2Y2, P2Y4 and P2Y6 agonist, which an be used for the research of cancer .
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Cat. No.: HY-174793
Target:  

mRNA

Research Areas:  

Others

The Cas9-T2A-GFP mRNA encodes a Cas9 nuclease gene with two nuclear localization signals (NLS) and a green fluorescent protein (GFP), which could be used in genome engineering experiments. The incorporation of N1-Methylpseudo-UTP can reduce the immunogenicity of the resulting mRNA.
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Cat. No.: HY-134352
CAS No.: 85280-66-6
AA-UTP tetrasodium is an amine-modified nucleotide that can be directly incorporated into labeled-UTP (HY-107372) .
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Cat. No.: HY-W011425B
NTP 25 mM Solution, PCR Grade is a mixed solution composed of 25 mM ATP (HY-B2176), 25 mM CTP (HY-125818), 25 mM GTP (HY-113225) and 25 mM UTP (HY-107372), free of DNase, RNase, phosphatase and protease. NTP 25 mM Solution, PCR Grade serves as an energy substrate and raw material for nucleic acid synthesis (DNA/RNA), and can also regulate the advanced structure of DNA to turn transcription on or off .
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