69199-40-2
Chemical Structure
3'-Deoxyuridine-5'-triphosphate
Synonym(s): 3'-dUTP
- CAS No.: 69199-40-2
- Formula:C9H15N2O14P3
- Molecular Weight:468.14
IUPAC Name: ((2S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate
InChIKey: PZBOEXFLRXEPHC-SHYZEUOFSA-N
SMILES: O=P(O)(O)OP(OP(OC[C@@H](O1)C[C@@H](O)[C@@H]1N2C(NC(C=C2)=O)=O)(O)=O)(O)=O
Biological Activity: 3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM[1].
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3'-Deoxyuridine-5'-triphosphate | 3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM. | |||||||||||||||||||||
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Keywords
