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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
135 Results for "
Quorum-sensing
" in MedChemExpress (MCE) Product Catalog:
Products (135)
135 Results for "Quorum-sensing" in MCE Product Catalog:
Cat. No.: HY-W045071
CAS No.: 106983-28-2
N-Hexanoyl-DL-homoserine lactone is a bacterial quorum sensing molecule produced in the rhizosphere. N-Hexanoyl-DL-homoserine lactone, a bacterial quorum sensing signal, induces transcriptional changes in Arabidopsis and may contribute to tuning plant growth to the microbial composition of the rhizosphere .
Cat. No.: HY-W342499
CAS No.: 55682-83-2
Synonyms: Methyl 3-hydroxytetradecanoate; 3-OH PAME; Methyl 3-hydroxymyristate
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3-Hydroxy myristic acid methyl ester (Methyl 3-hydroxytetradecanoate) is the quorum-sensing signal molecule (quormone), which regulates the virulence of Ralstonia solanacearum .
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Terrein is a melanogenesis inhibitor . Terrein induces apoptosis in breast cancer cell lines . Terrein is an inhibitor of quorum sensing and c-di-GMP in Pseudomonas aeruginosa .
Cat. No.: HY-W010608
CAS No.: 3188-00-9
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Cat. No.: HY-W012572
CAS No.: 351-50-8
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D-Histidine is an anti-biofilm agent that targets bacterial quorum sensing systems (such as RhlI/RhlR pathway) and has antibacterial activity. D-Histidine works by non-covalently binding to bacterial regulatory factors or copper ion complexes, selectively inhibiting bacterial biofilm formation and motility. D-Histidine downregulates quorum sensing-related gene expression, reduces the synthesis of virulence factors (such as alginate and proteases), and interferes with bacterial membrane stability, inhibiting biofilm formation, promoting the disintegration of mature biofilms, and enhancing antibiotic sensitivity. D-Histidine is also an efficient catalyst for the salt-induced peptide formation (SIPF) reaction, which promotes the condensation of amino acids to form dipeptides (such as dialanine and dilysine) by forming a complex with copper ions (Cu 2+) .
Cat. No.: HY-P2522
CAS No.: 1174553-84-4
Cat. No.: HY-N2795
CAS No.: 35349-68-9
Synonyms: Xanthone I
9-Hydroxycalabaxanthone (Xanthone I) is a known xanthone isolated from Garcinia mangostana Linn. 9-Hydroxycalabaxanthone has quorum-sensing inhibitory, anti-microbial, and anti-malarial activities (IC50=1.2-1.5 μM) .
N-(Ketocaproyl)-DL-homoserine lactone is a natural, very active ligand of LuxR. N-(Ketocaproyl)-DL-homoserine lactone is a quorum sensing (QS) autoinducer .
Cat. No.: HY-P11175
CAS No.: 438620-89-4
QStatin is a potent and selective inhibitor of SmcR (V. harveyi LuxR homologue) with an EC50 of 208.9 nM, binding tightly to SmcR and changes the flexibility of the protein, thereby altering its transcription regulatory activity. QStatin shows pan-QS (Vibrio quorum sensing) inhibitor activity in diverse Vibrio species and attenuates their virulence in an aquatic host. QStatin may be a sustainable antivibriosis agent useful in aquacultures .
Cat. No.: HY-W015800
CAS No.: 2185-03-7
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Synonyms: 3-Oxo-C14-AHL
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Synonyms: 3-Oxo-C10-HSL
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Synonyms: (+)-Ambuic acid
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Cat. No.: HY-Y0248AS
CAS No.: 166447-71-8
Synonyms: trans,trans-Farnesol-d6; (2E,6E)-Farnesol-d6
Cat. No.: HY-P2145
CAS No.: 960129-66-2
Synonyms: EDF
Cat. No.: HY-W012927
CAS No.: 19322-27-1
Synonyms: Chicory furaneol
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4-Hydroxy-5-methylfuran-3 (2H)-one (Chicory furaneol) is a mimic of bacterial quorum-sensing autoinducer AI-2. 4-Hydroxy-5-methylfuran-3 (2H)-one is produced by the yeast Saccharomyces cerevisiae, can be recognized by the AI-2 receptor LuxP of Vibrio harveyi and activate the AI-2-associated quorum-sensing signaling pathway, and is used for studying cross-species chemical communication and quorum-sensing mechanisms .
Cat. No.: HY-134215
CAS No.: 677354-23-3
cis-11-Methyl-2-dodecenoic acid is a quorum sensing (QS) signal that acts as a diffusion signaling factor (DSF) in extracellular microbial and fungal communication systems. DSF is involved in the regulation of virulence and biofilm formation of a variety of bacterial pathogens .
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2,3,4-Trihydroxybenzophenone is a hydroxylated benzophenone UV filter with estrogenic activity. 2,3,4-Trihydroxybenzophenone is a quorum sensing inhibitor and an EC 1.14.18.1 (tyrosinase) inhibitor. 2,3,4-Trihydroxybenzophenone is also a human urinary metabolite, a rat metabolite and a drug metabolite .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
