582-46-7
Chemical Structure
Terrein
- CAS No.: 582-46-7
- Formula:C8H10O3
- Molecular Weight:154.16
IUPAC Name: (4S,5R)-4,5-dihydroxy-3-((E)-prop-1-en-1-yl)cyclopent-2-en-1-one
InChIKey: MHOOPNKRBMHHEC-HZIBQTDNSA-N
SMILES: O=C1C=C(/C=C/C)[C@H](O)[C@H]1O
Biological Activity: Terrein is a melanogenesis inhibitor[1]. Terrein induces apoptosis in breast cancer cell lines [2]. Terrein is an inhibitor of quorum sensing and c-di-GMP in Pseudomonas aeruginosa[3].
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Terrein | 99.44% | Terrein is a melanogenesis inhibitor. Terrein induces apoptosis in breast cancer cell lines . Terrein is an inhibitor of quorum sensing and c-di-GMP in Pseudomonas aeruginosa. | ||||||||||||||||||||
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- [1]. S-H Park, et al. Terrein: A New Melanogenesis Inhibitor and Its Mechanism. Cell Mol Life Sci. 2004 Nov;61(22):2878-85. [Content Brief]
- [2]. Anongnard Kasorn, et al. Terrein Inhibits Migration of Human Breast Cancer Cells via Inhibition of the Rho and Rac Signaling Pathways. Oncol Rep. 2018 Mar;39(3):1378-1386. [Content Brief]
- [3]. Bomin Kim, et al. Terrein Is an Inhibitor of Quorum Sensing and c-di-GMP in Pseudomonas Aeruginosa: A Connection Between Quorum Sensing and c-di-GMP. Sci Rep. 2018 Jun 5;8(1):8617. [Content Brief]
Keywords