1174553-84-4
Chemical Structure
Competence-Stimulating Peptide-2 (CSP-2)
- CAS No.: 1174553-84-4
- Formula:C101H172N28O23S
- Molecular Weight:2178.69
InChIKey: VNWKTOKETHGBQD-UHFFFAOYSA-N
SMILES: NCCCC[C@@H](C(O)=O)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H](CC1=CC=CC=C1)NC([C@H](CC(C)C)NC([C@@H](NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC([C@H]([C@@H](C)CC)NC([C@H]([C@@H](C)CC)NC([C@H](CCCNC(N)=N)NC([C@H](CO)NC([C@H]([C@@H](C)CC)NC([C@H](CCCNC(N)=N)NC([C@H](CCSC)NC([C@@H](N)CCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O)=O)=O
Biological Activity: Competence-Stimulating Peptide-2 (CSP-2) is a 17-amino acid signal peptide produced by Streptococcus pneumoniae, with an EC50 of 50.7 nM for its compatible receptor ComD2. Competence-Stimulating Peptide-2 (CSP-2) can regulate bacterial phenotypes such as competence development, virulence, and biofilm formation through quorum sensing[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Competence-Stimulating Peptide-2 (CSP-2) | 99.45% | Competence-Stimulating Peptide-2 (CSP-2) is a 17-amino acid signal peptide produced by Streptococcus pneumoniae, with an EC50 of 50.7 nM for its compatible receptor ComD2. Competence-Stimulating Peptide-2 (CSP-2) can regulate bacterial phenotypes such as competence development, virulence, and biofilm formation through quorum sensing. | ||||||||||||||||||||
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References
- [1]. Yifang Yang, et al. Structural Characterization of Competence-Stimulating Peptide Analogues Reveals Key Features for ComD1 and ComD2 Receptor Binding in Streptococcus pneumonia. Biochemistry. 2018 Sep 11;57(36):5359-5369. [Content Brief]
- [2]. Bradshaw JL, et al. Transformation of nonencapsulated Streptococcus pneumoniae during systemic infection. Sci Rep. 2020 Nov 3;10(1):18932. [Content Brief]
