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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
474 Results for "
Insect
" in MedChemExpress (MCE) Product Catalog:
Products (474)
474 Results for "Insect" in MCE Product Catalog:
Cat. No.: HY-E72098
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Human CYP2C9, Reductase+b5 refers to a near-physiological recombinant microsomal system co-expressed in insect cells, which consists of human cytochrome P450 2C9, NADPH-P450 oxidoreductase (CPR) and cytochrome b5. Human CYP2C9 is a human cytochrome P450 subtype belonging to the CYP2 family, and also a major metabolic enzyme. It is predominantly expressed in human liver and can metabolize a variety of active compounds .
Cat. No.: HY-E72102
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Human CYP3A4, Reductase+b5 refers to a near-physiological recombinant microsomal system co-expressed in insect cells, consisting of human cytochrome P450 3A4, NADPH-P450 oxidoreductase (CPR) and cytochrome b5. Human CYP3A4 is a human cytochrome P450 subtype belonging to the CYP3 family, as well as a major metabolic enzyme. It is predominantly expressed in human liver and intestine, metabolizes a variety of active compounds, and activates multiple procarcinogens .
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Cat. No.: HY-W751266
CAS No.: 113565-32-5
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Cat. No.: HY-W739842
CAS No.: 17834-04-7
Synonyms: 8-OH Warfarin
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8-Hydroxywarfarin (8-OH Warfarin) is a CYP2C9 inhibitor. 8-Hydroxywarfarin inactivates the anticoagulant activity of Warfarin (HY-B0687) via 8-hydroxylation. 8-Hydroxywarfarin serves as a glucuronidation substrate for UGT1A1, UGT1A8, UGT1A9, as well as wild-type/mutant UGT1A10. This reaction enhances its polarity, solubility and excretion efficiency, and the process is independent of phenylalanine 90 of UGT1A10. 8-Hydroxywarfarin can be used in studies related to thromboembolic diseases .
Cat. No.: HY-17516R
CAS No.: 129558-76-5
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Tolfenpyrad (Standard) is the analytical standard of Tolfenpyrad (HY-17516). This product is intended for research and analytical applications. Tolfenpyrad is an orally active insecticide, acaricide and antibacterial agent. Tolfenpyrad inhibits Complex I in the mitochondrial respiratory electron transport chain, interfering with the cell respiration process. Tolfenpyrad has significant insecticidal activity against a variety of insect pests such as H. contortus, Coccinella septempunctata. Tolfenpyrad has antibacterial activity against Francisella novicida, with an IC50 of 1.2 µM or 1.5 µM .
Cat. No.: HY-E72095
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Human CYP2A6, Reductase+b5 refers to a near-physiological recombinant microsomal system co-expressed in insect cells, which consists of human cytochrome P450 2A6, NADPH-P450 oxidoreductase (CPR) and cytochrome b5. Human CYP2A6 is a human cytochrome P450 subtype belonging to the CYP2 family, as well as a major metabolic enzyme. It is predominantly expressed in human liver and metabolizes a variety of active compounds including Coumarin (HY-N0709) and nicotine .
Cat. No.: HY-E72101
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Human CYP2E1, Reductase+b5 refers to a near-physiological recombinant microsomal system co-expressed in insect cells, which consists of human cytochrome P450 2E1, NADPH-P450 oxidoreductase (CPR), and cytochrome b5. Human CYP2E1 is a human cytochrome P450 subtype belonging to the CYP2 family, and also a major oxidase. Its expression is centered in human liver, and can be induced in the brain (neurons, astrocytes, cerebellar granule cells), lung and kidney .
Cat. No.: HY-E72103
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Human CYP1A1, Reductase+b5 refers to a near-physiological recombinant microsomal system co-expressed in insect cells, consisting of human cytochrome P450 1A1, NADPH-P450 oxidoreductase (CPR) and cytochrome b5. Human CYP1A1 is a human cytochrome P450 subtype belonging to the CYP1 family, as well as a major metabolic enzyme. Its expression is concentrated in tissues such as lung, breast, placenta and endometrium, and it can metabolize polycyclic aromatic hydrocarbons and estrogens into carcinogenic intermediates with DNA-damaging activity .
Cat. No.: HY-W010435R
CAS No.: 110-93-0
Synonyms: 6-Methyl-5-hepten-2-one (Standard)
Cat. No.: HY-W747972A
CAS No.: 6789-80-6
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Cat. No.: HY-E72116
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Human UGT2B4 is a UDP-glucuronosyltransferase. UGT2B4 catalyzes the glucuronidation of bile acids, Carvedilol (HY-B0006) and 6-hydroxylated bile acids to form glucuronide derivatives. UGT2B4 participates in the inactivation of endogenous and exogenous substances, including catechol estrogens, C19 steroids, phenols and monoterpenoids. Human UGT2B4 can be used in the research of hypertension, angina pectoris, chronic heart failure and intrahepatic cholestasis .
Cat. No.: HY-128421R
CAS No.: 505-52-2
Synonyms: Brassylic Acid (Standard)
Cat. No.: HY-183957
CAS No.: 96883-54-4
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(Z,E)-7,11-Hexadecadienal is a geometric isomer of Z7,Z11-16:Ald, the core component of the citrus leafminer sex pheromone. (Z,E)-7,11-Hexadecadienal acts as a sex pheromone tropism inhibitor; when mixed with the sex pheromone Z7,Z11-16:Ald, it blocks the tropism of male citrus leafminers towards the sex pheromone component. (Z,E)-7,11-Hexadecadienal can be used in insect resistance-related research .
Cat. No.: HY-B0824R
CAS No.: 82657-04-3
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Bifenthrin (Standard) is the analytical standard of Bifenthrin. This product is intended for research and analytical applications. Bifenthrin is a synthetic pyrethroid insecticide. Bifenthrin prolongs the opening time of Nav1.8 sodium channels, leading to membrane depolarization and conductance block in the insect nervous system, thereby disrupting neural function. Bifenthrin was effective in inhibiting A. gambiae (LD50=0.15 ng/mg) and C. quinquefasciatus (LD50=0.16 ng/mg). Bifenthrin has good lethality against susceptible and resistant mosquitoes and is very effective in inhibiting blood sucking and can be developed as a mosquito-removal netting material .
Cat. No.: HY-B0874
CAS No.: 67375-30-8
Synonyms: FMC 45497; Fendona; WL 85871
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Alpha-Cypermethrin (FMC 45497; Fendona; WL 85871) is a type II pyrethroid insecticide. Alpha-Cypermethrin acts by delaying the inactivation of voltage-gated sodium channels, prolonging sodium tail currents, and triggering repetitive neural discharges. Alpha-Cypermethrin exhibits knockdown and lethal activity against target insects such as Musca domestica and Anopheles culicifacies. Alpha-Cypermethrin induces neurotoxicity in mammals, alters placental and fetal neurodevelopment, and causes acute mortality in fish. Alpha-Cypermethrin can be used in studies related to neurotoxicity, vector-borne diseases, and malaria .
Cat. No.: HY-E72100
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Human CYP2D6, Reductase+b5 refers to a near-physiological recombinant microsomal system co-expressed in insect cells, consisting of human cytochrome P450 2D6, NADPH-P450 oxidoreductase (CPR) and cytochrome b5. Human CYP2D6 is a human cytochrome P450 subtype belonging to the CYP2 family, and also serves as a major metabolic enzyme capable of crossing the blood-brain barrier. Its expression is centered in the human liver (also detected in the brain) and exhibits high polymorphism .
Cat. No.: HY-N7400
CAS No.: 118555-82-1
Cat. No.: HY-W017141
CAS No.: 24683-00-9
Category:
Natural Products Other Diseases Vitis vinifera cv. Zalema Plants Vitaceae Disease Research Fields
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Cat. No.: HY-W108418
CAS No.: 40642-40-8
Synonyms: cis-8-Dodecen-1-ol
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
