(Z)-8-Dodecen-1-ol
Based on 1 Customer Validation
(Z)-8-Dodecen-1-ol (cis-8-Dodecen-1-ol) is an insect pheromone agonist and attractant active substance. (Z)-8-Dodecen-1-ol serves as the main component of the sex pheromone gland in female Cryptophlebia horii, exhibits stable attractant activity towards male moths, and induces significant electroantennogram signals. (Z)-8-Dodecen-1-ol can be used in studies related to male moth trapping and pest control.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 40642-40-8
- Formula: C12H24O
- Molecular Weight:184.32
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
(Z)-8-Dodecen-1-ol (0.1-10 ng; 15 min, overnight) acts as the major sex pheromone component of female Cryptophlebia horii, elicits strong EAG responses from male Cryptophlebia horii antennae at low doses, and has a titer of ca. 4 ng per female[1].
(Z)-8-Dodecen-1-ol (10 ng) elicits weak EAG responses from male Cryptophlebia palustris antennae[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
(Z)-8-Dodecen-1-ol formulated sex pheromone mixtures of Grapholita molesta (0.1-500 μg; treated via gas phase volatile stimulation) induce significant electroantennogram (EAG) responses in the antennae of male Lyonetia clerkella[3].
(Z)-8-Dodecen-1-ol formulated sex pheromone mixtures of Grapholita molesta (50.0 μg per trap, weekly monitoring for 8 consecutive weeks) maintain stable and potent field trapping efficacy against male G. molesta, and the relative trapping efficiency shows no obvious decline after blending with Lyonetia clerkella sex pheromones[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Cryptophlebia horii (2- to 3-d-old)[1]
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Dosage:0.1 ng, 1 ng, 10 ng
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Administration:volatile exposure via GC effluent
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Result:Exhibited maximum average EAG activity among all tested pheromone components at 0.1 ng.
Failed to trigger dose-dependent EAG elevation, with weaker responses than (E)-8-dodecen-1-ol at 1 ng and 10 ng.
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Animal Model:male moths (2-3 days post-emergence)[3]
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Dosage:0.1 μg, 1.0 μg, 10.0 μg, 100.0 μg, 500.0 μg (as part of 95:5:5 Grapholitha molesta sex pheromone blend)
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Administration:volatile air stimulation
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Result:Evoked elevated EAG responses versus paraffin oil control across all test dosages.
Attained peak EAG responses at 0.1 μg and 1.0 μg.
Produced weaker EAG signals at 10.0 μg, 100.0 μg and 500.0 μg relative to 0.1-1.0 μg treatments.
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Animal Model:male moths (2-3 days post-emergence)[3]
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Dosage:50.0 μg (as part of 95:5:5 Grapholitha molesta sex pheromone blend; tested alone and mixed with 1.0 mg or 2.0 mg Lyonetia clerkella sex pheromone)
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Administration:per trap; weekly surveys for 8 weeks
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Result:Captured 28.8 Grapholita molesta moths per trap weekly alone, with a 35.17% relative trapping rate.
Captured 17.4 and 24.3 moths weekly when blended with 1.0 mg and 2.0 mg Lyonetia clerkella sex pheromone, corresponding to 17.89% and 22.98% relative trapping rates.
Displayed comparable trapping efficiency across all test groups.
Chemical Information
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CAS No. 40642-40-8
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Appearance Liquid (Density: 0.847±0.06 g/cm3)
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Molecular Weight 184.32
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Formula C12H24O
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Color Colorless to light yellow
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SMILES
CCC/C=C\CCCCCCCO
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Synonyms
cis-8-Dodecen-1-ol
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Structure Classification
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Initial Source
Laspeyresia pomonella
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (542.53 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.4253 mL | 27.1267 mL | 54.2535 mL | 135.6337 mL |
| 5 mM | 1.0851 mL | 5.4253 mL | 10.8507 mL | 27.1267 mL | |
| 10 mM | 0.5425 mL | 2.7127 mL | 5.4253 mL | 13.5634 mL | |
| 15 mM | 0.3617 mL | 1.8084 mL | 3.6169 mL | 9.0422 mL | |
| 20 mM | 0.2713 mL | 1.3563 mL | 2.7127 mL | 6.7817 mL | |
| 25 mM | 0.2170 mL | 1.0851 mL | 2.1701 mL | 5.4253 mL | |
| 30 mM | 0.1808 mL | 0.9042 mL | 1.8084 mL | 4.5211 mL | |
| 40 mM | 0.1356 mL | 0.6782 mL | 1.3563 mL | 3.3908 mL | |
| 50 mM | 0.1085 mL | 0.5425 mL | 1.0851 mL | 2.7127 mL | |
| 60 mM | 0.0904 mL | 0.4521 mL | 0.9042 mL | 2.2606 mL | |
| 80 mM | 0.0678 mL | 0.3391 mL | 0.6782 mL | 1.6954 mL | |
| 100 mM | 0.0543 mL | 0.2713 mL | 0.5425 mL | 1.3563 mL |
(Z)-8-Dodecen-1-ol Related Classifications
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