(Z)-8-Dodecen-1-ol (Synonyms: cis-8-Dodecen-1-ol)

Cat. No.: HY-W108418 Purity: 98.0%: Data Sheet
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(Z)-8-Dodecen-1-ol (cis-8-Dodecen-1-ol) is an insect pheromone agonist and attractant active substance. (Z)-8-Dodecen-1-ol serves as the main component of the sex pheromone gland in female Cryptophlebia horii, exhibits stable attractant activity towards male moths, and induces significant electroantennogram signals. (Z)-8-Dodecen-1-ol can be used in studies related to male moth trapping and pest control.

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(Z)-8-Dodecen-1-ol Chemical Structure

CAS No. : 40642-40-8

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Description

In Vitro

(Z)-8-Dodecen-1-ol (0.1-10 ng; 15 min, overnight) acts as the major sex pheromone component of female Cryptophlebia horii, elicits strong EAG responses from male Cryptophlebia horii antennae at low doses, and has a titer of ca. 4 ng per female^[1].
(Z)-8-Dodecen-1-ol (10 ng) elicits weak EAG responses from male Cryptophlebia palustris antennae^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

(Z)-8-Dodecen-1-ol (1.00 mg/rubber septum; slow-release volatile; continuous exposure) is indispensable for attracting male Cryptophlebia horii moths. When used alone at a dose of 1.00 mg per lure, the maximum catch per trap reaches 380 male moths^[1].
(Z)-8-Dodecen-1-ol formulated sex pheromone mixtures of Grapholita molesta (0.1-500 μg; treated via gas phase volatile stimulation) induce significant electroantennogram (EAG) responses in the antennae of male Lyonetia clerkella^[3].
(Z)-8-Dodecen-1-ol formulated sex pheromone mixtures of Grapholita molesta (50.0 μg per trap, weekly monitoring for 8 consecutive weeks) maintain stable and potent field trapping efficacy against male G. molesta, and the relative trapping efficiency shows no obvious decline after blending with Lyonetia clerkella sex pheromones^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Male Cryptophlebia horii (2- to 3-d-old)^[1]
Dosage:	0.1 ng, 1 ng, 10 ng
Administration:	volatile exposure via GC effluent
Result:	Exhibited maximum average EAG activity among all tested pheromone components at 0.1 ng. Failed to trigger dose-dependent EAG elevation, with weaker responses than (E)-8-dodecen-1-ol at 1 ng and 10 ng.

Animal Model:	male moths (2-3 days post-emergence)^[3]
Dosage:	0.1 μg, 1.0 μg, 10.0 μg, 100.0 μg, 500.0 μg (as part of 95:5:5 Grapholitha molesta sex pheromone blend)
Administration:	volatile air stimulation
Result:	Evoked elevated EAG responses versus paraffin oil control across all test dosages. Attained peak EAG responses at 0.1 μg and 1.0 μg. Produced weaker EAG signals at 10.0 μg, 100.0 μg and 500.0 μg relative to 0.1-1.0 μg treatments.

Animal Model:	male moths (2-3 days post-emergence)^[3]
Dosage:	50.0 μg (as part of 95:5:5 Grapholitha molesta sex pheromone blend; tested alone and mixed with 1.0 mg or 2.0 mg Lyonetia clerkella sex pheromone)
Administration:	per trap; weekly surveys for 8 weeks
Result:	Captured 28.8 Grapholita molesta moths per trap weekly alone, with a 35.17% relative trapping rate. Captured 17.4 and 24.3 moths weekly when blended with 1.0 mg and 2.0 mg Lyonetia clerkella sex pheromone, corresponding to 17.89% and 22.98% relative trapping rates. Displayed comparable trapping efficiency across all test groups.

Molecular Weight

184.32

Formula

C₁₂H₂₄O

CAS No.

40642-40-8

Appearance

Liquid (Density: 0.847±0.06 g/cm³)

Color

Colorless to light yellow

SMILES

CCC/C=C\CCCCCCCO

Structure Classification

Others

Initial Source

Animals

Laspeyresia pomonella

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (542.53 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.4253 mL	27.1267 mL	54.2535 mL
5 mM	1.0851 mL	5.4253 mL	10.8507 mL
10 mM	0.5425 mL	2.7127 mL	5.4253 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.0%

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Data Sheet (271 KB) SDS (393 KB)

COA (238 KB) HNMR (244 KB) MS (73 KB)

Handling Instructions (2659 KB)

References

[1]. Van Vang L, et al. Sex Pheromones of Five Olethreutine Species (Lepidoptera: Tortricidae) Associated with the Seedlings and Fruits of Mangrove Plants in the Ryukyu Islands, Japan: Identification and Field Evaluation. Journal of Chemical Ecology. 2005;31:859-878. [Content Brief]

[2]. Guerin PM, et al. Sex pheromone of Grapholita funebrana occurrence of Z-8- and Z-10-Tetradecenyl acetate as secondary components. Journal of Chemical Ecology. 1986;12:1361-1368.

[3]. Sun Y, et al. Interaction effects of sex pheromones between Lyonetia clerkella and Grapholita molesta. Journal of Fruit Science. 2021;38(9):1563-1568.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.4253 mL	27.1267 mL	54.2535 mL	135.6337 mL
	5 mM	1.0851 mL	5.4253 mL	10.8507 mL	27.1267 mL
	10 mM	0.5425 mL	2.7127 mL	5.4253 mL	13.5634 mL
	15 mM	0.3617 mL	1.8084 mL	3.6169 mL	9.0422 mL
	20 mM	0.2713 mL	1.3563 mL	2.7127 mL	6.7817 mL
	25 mM	0.2170 mL	1.0851 mL	2.1701 mL	5.4253 mL
	30 mM	0.1808 mL	0.9042 mL	1.8084 mL	4.5211 mL
	40 mM	0.1356 mL	0.6782 mL	1.3563 mL	3.3908 mL
	50 mM	0.1085 mL	0.5425 mL	1.0851 mL	2.7127 mL
	60 mM	0.0904 mL	0.4521 mL	0.9042 mL	2.2606 mL
	80 mM	0.0678 mL	0.3391 mL	0.6782 mL	1.6954 mL
	100 mM	0.0543 mL	0.2713 mL	0.5425 mL	1.3563 mL

(Z)-8-Dodecen-1-ol Related Classifications

Infection

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(Z)-8-Dodecen-1-ol40642-40-8cis-8-Dodecen-1-olSex PheromoneInsecticideGrapholita funebranasex pheromone gland extractantennaePammene rhediellaCryptophlebia palustrisGrapholita molestaCryptophlebia horiielectroantennographic responsesLyonetia clerkellasex pheromone blendInhibitorinhibitorinhibit

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(Z)-8-Dodecen-1-ol (Synonyms: cis-8-Dodecen-1-ol)

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