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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
474 Results for "
Insect
" in MedChemExpress (MCE) Product Catalog:
Products (474)
474 Results for "Insect" in MCE Product Catalog:
Cat. No.: HY-184009
CAS No.: 892237-40-0
Target:
Research Areas:
TBZ-15 is an orally active competitive Chitinase inhibitor and Insecticide, with an IC50 of 1.00 μM against Ostrinia furnacalis Chitinase-h and an IC50 of 1.01 μM against Ostrinia furnacalis Chitinase-I. TBZ-15 exhibits insecticidal activity against the Asian corn borer (O. furnacalis) and the diamondback moth (P. xylostella) .
Cat. No.: HY-W108419A
CAS No.: 38421-90-8
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trans-5-Decenyl acetate is a synthetic sex pheromone component. trans-5-Decenyl acetate attracts male Anarsia lineatella moths when used in a mixture with trans-5-decen-1-ol (HY-W127516). trans-5-Decenyl acetate can be used to monitor male Anarsia lineatella moth activity in peach and almond orchard field .
Cat. No.: HY-B0874R
CAS No.: 67375-30-8
Synonyms: FMC 45497 (Standard); Fendona (Standard); WL 85871 (Standard)
Alpha-Cypermethrin (Standard) (FMC 45497 (Standard); Fendona (Standard); WL 85871 (Standard)) is the analytical standard of Alpha-Cypermethrin (HY-B0874). This product is intended for research and analytical applications. Alpha-Cypermethrin (FMC 45497; Fendona; WL 85871) is a type II pyrethroid insecticide. Alpha-Cypermethrin acts by delaying the inactivation of voltage-gated sodium channels, prolonging sodium tail currents, and triggering repetitive neural discharges. Alpha-Cypermethrin exhibits knockdown and lethal activity against target insects such as Musca domestica and Anopheles culicifacies. Alpha-Cypermethrin induces neurotoxicity in mammals, alters placental and fetal neurodevelopment, and causes acute mortality in fish. Alpha-Cypermethrin can be used in studies related to neurotoxicity, vector-borne diseases, and malaria .
Cat. No.: HY-W017141R
CAS No.: 24683-00-9
Cat. No.: HY-W017141S1
CAS No.: 3028868-76-7
Cat. No.: HY-E72112
Human UGT1A10 is a UDP-glucuronosyltransferase. UGT1A10 catalyzes the glucuronidation of Mycophenolic acid (HY-B0421). Human UGT1A10 mediates glucuronidation modification of 34 out of 42 tested bioflavonoids. Human UGT1A10 is applicable to relevant research on colorectal cancer .
Cat. No.: HY-P5391
CAS No.: 717919-61-4
Cat. No.: HY-E70277
CAS No.: 71425-89-3
Research Areas:
Hexadecyl-CoA is a non-hydrolyzable thioether analog of Palmitoyl-CoA. Hexadecyl-CoA competitively inhibits the acyl-CoA thioesterase activity of HNF-4α with a Ki of 0.3 μM, and inhibits DGAT2 activity with an IC50 of approximately 2 μM. Hexadecyl-CoA also inhibits ATGL activity and serves as a reference inhibitor for DGAT2 LC/MS enzyme activity assays. Hexadecyl-CoA can be used in studies related to lipid metabolism, triglyceride synthesis and lipolysis .
Cat. No.: HY-W587734
CAS No.: 203312-38-3
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Spirotetramat-enol, Spirotetramat (HY-120253) metabolite, is an insecticide. Spirotetramat-enol shows inhibitory activity against acetyl-CoA carboxylase. Spirotetramat-enol exerts insecticidal activity against Aphis craccivora Koch .
Cat. No.: HY-16676
CAS No.: 153381-68-1
Synonyms: 4-epi-Docetaxel; 7-Epidocetaxel; 7-Epitaxotere
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Research Areas:
7-Epi-docetaxel (4-epi-Docetaxel; 7-Epidocetaxel; 7-Epitaxotere) is the major C7 epimeric impurity/in vivo metabolite of Docetaxel (HY-B0011). 7-Epi-docetaxel acts as a potent allosteric activator of rhCYP1B1. 7-Epi-docetaxel exhibits certain cell line-specific anti-migratory activity . 7-Epi-docetaxel can be used in research related to melanoma and lung adenocarcinoma .
Cat. No.: HY-153507
CAS No.: 1137671-16-9
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Research Areas:
DGAT1-IN-4 is a potent, orally active, and selective DGAT1 inhibitor with an IC50 of 17 nM. DGAT1-IN-4 exhibits >588-fold selectivity over DGAT2. DGAT1-IN-4 suppresses intracellular triglyceride synthesis in mouse myoblast cells. DGAT1-IN-4 suppresses body weight gain in diet-induced obese dogs. DGAT1-IN-4 can be used for the research of obesity .
Cat. No.: HY-L190
1,661 compounds
Miao medicine is an important part of Chinese medicine, which carries the profound cultural heritage and rich life wisdom of the Hmongb people. Miao people live in a concentrated community in the mountainous area of the southwest border of China, which has a unique natural environment. Complex and diverse geology, lush natural vegetation, rich animal and plant species, a large number of mineral resources which provide a wide range of species sources for miao ethnicity medicine. On the other hand, due to the characteristics of the living environment of the Hmongb people, Miao medicine has demonstrated its unique therapeutic effect in the treatment of some endemic diseases, infectious diseases, insect, snake and beast bites, rheumatism and other diseases. With the development of modern science and technology, the research and application of seedling medicine are also deepening. Through the systematic study of the chemical composition and pharmacological action of the seedling medicine, it can provide a new idea and method for modern medicine.
MCE included 1,661 natural products from traditional miao ethnicity medicine, including animal, plant and mineral sources.
Cat. No.: HY-171722
CAS No.: 1355681-08-1
Synonyms: Asc-C9
Target:
Ascr#10 (Asc-C9) is an orally active thermogenesis inducer and insecticide that can be obtained from Monochamus alternatus. Ascr#10 binds to the insect adipokinetic hormone (AKH) receptor (Ka=272 µM) and stimulates mitochondrial biogenesis via the PGC1α-UCP4 axis. Consequently, Ascr#10 induces UCP4-mediated uncoupled respiration, reduces the ATP/ADP ratio and accelerates lipid mobilization, thereby driving the thermogenesis process. Ascr#10 delays pupation and exerts specific chemotaxis toward dispersive fourth-stage pinewood nematode LIV larvae. Ascr#10 promotes cold acclimation of Monochamus alternatus larvae through metabolic inhibition and cryoprotectant accumulation, enhancing their survival rate under cold stress. Ascr#10 also induces browning of white adipose tissue and activates brown adipose tissue in mice, thereby helping the body resist cold and tumor growth. Ascr#10 can be widely applied to research related to pine wilt disease, lung tumors and cold stress .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
