67375-30-8
Chemical Structure
Alpha-Cypermethrin
Synonym(s): FMC 45497; Fendona; WL 85871
- CAS No.: 67375-30-8
- Formula:C22H19Cl2NO3
- Molecular Weight:416.30
IUPAC Name: (R)-cyano(3-phenoxyphenyl)methyl (1S,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane-1-carboxylate
InChIKey: KAATUXNTWXVJKI-WSTZPKSXSA-N
SMILES: O=C([C@@H]1C(C)(C)[C@@H]1/C=C(Cl)\Cl)O[C@@H](C#N)C2=CC=CC(OC3=CC=CC=C3)=C2
Biological Activity: Alpha-Cypermethrin (FMC 45497; Fendona; WL 85871) is a type II pyrethroid insecticide. Alpha-Cypermethrin acts by delaying the inactivation of voltage-gated sodium channels, prolonging sodium tail currents, and triggering repetitive neural discharges. Alpha-Cypermethrin exhibits knockdown and lethal activity against target insects such as Musca domestica and Anopheles culicifacies. Alpha-Cypermethrin induces neurotoxicity in mammals, alters placental and fetal neurodevelopment, and causes acute mortality in fish. Alpha-Cypermethrin can be used in studies related to neurotoxicity, vector-borne diseases, and malaria[1][2][3][4][5][6].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Alpha-Cypermethrin | 99.66% | Alpha-Cypermethrin (FMC 45497; Fendona; WL 85871) is a type II pyrethroid insecticide. Alpha-Cypermethrin acts by delaying the inactivation of voltage-gated sodium channels, prolonging sodium tail currents, and triggering repetitive neural discharges. Alpha-Cypermethrin exhibits knockdown and lethal activity against target insects such as Musca domestica and Anopheles culicifacies. Alpha-Cypermethrin induces neurotoxicity in mammals, alters placental and fetal neurodevelopment, and causes acute mortality in fish. Alpha-Cypermethrin can be used in studies related to neurotoxicity, vector-borne diseases, and malaria. | ||||||||||||||||||||
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Alpha-Cypermethrin (Standard) | ≥98% | Alpha-Cypermethrin (Standard) (FMC 45497 (Standard); Fendona (Standard); WL 85871 (Standard)) is the analytical standard of Alpha-Cypermethrin (HY-B0874). This product is intended for research and analytical applications. Alpha-Cypermethrin (FMC 45497; Fendona; WL 85871) is a type II pyrethroid insecticide. Alpha-Cypermethrin acts by delaying the inactivation of voltage-gated sodium channels, prolonging sodium tail currents, and triggering repetitive neural discharges. Alpha-Cypermethrin exhibits knockdown and lethal activity against target insects such as Musca domestica and Anopheles culicifacies. Alpha-Cypermethrin induces neurotoxicity in mammals, alters placental and fetal neurodevelopment, and causes acute mortality in fish. Alpha-Cypermethrin can be used in studies related to neurotoxicity, vector-borne diseases, and malaria. | ||||||||||||||||||||
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References
- [1]. Elsawy H, et al. Protective effect of α-lipoic acid against α-cypermethrin-induced changes in rat cerebellum. Journal of chemical neuroanatomy. 2017 Dec;86:52-58.
- [2]. World Health Organization. Alpha-cypermethrin[M]. World Health Organization, 1992.
- [3]. Abbas N, et al. Alpha-Cypermethrin Resistance in Musca domestica: Resistance Instability, Realized Heritability, Risk Assessment, and Insecticide Cross-Resistance. Insects. 2023 Feb 26;14(3):233. [Content Brief]
- [4]. Elser BA, et al. Maternal α-cypermethrin and permethrin exert differential effects on fetal growth, placental morphology, and fetal neurodevelopment in mice. Toxicological sciences : an official journal of the Society of Toxicology. 2025 Sep 01;207(1):91-108.
- [5]. Shires SW. Toxicity of a new pyrethroid insecticide, WL85871, to rainbow trout. Bull Environ Contam Toxicol. 1985 Jan;34(1):134-7.
- [6]. Ansari MA, et al. Bio-efficacy and operational feasibility of alphacypermethrin (Fendona) impregnated mosquito nets to control rural malaria in northern India. Journal of vector borne diseases. 2003;40(1-2):33-42.
