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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
172 Results for "
AIDs
" in MedChemExpress (MCE) Product Catalog:
Products (172)
172 Results for "AIDs" in MCE Product Catalog:
Cat. No.: HY-174303
Target:
Research Areas:
NNRT-IN-9 (Compound EG28) is a non-nucleoside reverse transcriptase (NNRT) inhibitor. NNRT-IN-9 has potent antiviral and anti-resistance activity against wild-type (WT) HIV-1 and various clinically relevant mutations (E138K and K103N + Y181C) with EC50s of 55, 67 and 3910 nM, respectively. NNRT-IN-9 can be used for acquired immune deficiency syndrome (AIDS) research .
Cat. No.: HY-145569
CAS No.: 1818867-24-1
Synonyms: GSK3640254
Fipravirimat is a potent HIV-1 inhibitor. Fipravirimat has the potential for HIV and AIDS research .
Cat. No.: HY-177071
CAS No.: 2765212-92-6
Asuptegravir (Compound 1) is an inhibitor of HIV integrase activity. Asuptegravir inhibits HIV in HEK293T cells (EC50 = 1.08 nM). Asuptegravir can be studied in anti-AIDs/HIV research .
Cat. No.: HY-106155
CAS No.: 145514-04-1
Synonyms: DAPD
Target:
Research Areas:
Amdoxovir (DAPD) is an orally active nucleoside reverse transcriptase inhibitor. Amdoxovir is active against wild-type and NRTl-resistant viruses. Amdoxovir is the prodrug of dioxolane guanosine. Amdoxovir can be used for research of HIV/AIDS .
Cat. No.: HY-117879
CAS No.: 1515856-61-7
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PF-4776548 is a highly potent HIV integrase inhibitor. PF-477654 blocks the process of integrating HIV viral DNA into the host cell genome. PF-4776548 is promising for research of AIDS .
Cat. No.: HY-136548A
CAS No.: 2122333-63-3
Synonyms: TFV-DP triethylamine
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Tenofovir diphosphate triethylamine is an antiretroviral agent. Tenofovir diphosphate triethylamine is an inhibitor of HIV reverse transcriptase DNA (Ki = 1.55 μM) and RNA (Ki = 0.022 μM). Tenofovir diphosphate triethylamine can be used for the research of AIDS .
Cat. No.: HY-163852
CAS No.: 2801703-79-5
HIV-1 inhibitor-72 (compound 5m) is a target protein ligand of PROTAC Vif degrader-1 (HY-163851). HIV-1 inhibitor-72 is a potent HIV-1 inhibitor .
Category:
Cat. No.: HY-105098
CAS No.: 127759-89-1
Synonyms: BMS-180194; SQ 34514
Lobucavir (BMS-180194; SQ 34514)，a nucleoside analogue，is an antiviral agent. Lobucavir shows a broad spectrum of activity against HBV，HIV/AIDS，and α，β，and γ herpes viruses including CMV，herpes-simplex，varicella-zoster，and Epstein-Barr virus .
Cat. No.: HY-120880
CAS No.: 126333-28-6
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Cat. No.: HY-120712
CAS No.: 141979-04-6
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Ro 31-8588 is a HIV protease inhibitor with the Ki of 0.3 nM. Ro 31-8588 can be used for study of AIDS .
Cat. No.: HY-146088
CAS No.: 920036-04-0
HIV-1 inhibitor-31 (compound 4) is a potent HIV-1 inhibitor. HIV-1 inhibitor-31 can be used for researching AIDS .
Cat. No.: HY-151197
CAS No.: 2511547-82-1
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HIV protease-IN-1 (compound 1·succinate) is a potent HIV protease non-peptidic inhibitor, can be used to research AIDS .
Cat. No.: HY-10570S
CAS No.: 1051418-95-1
Cat. No.: HY-125712
CAS No.: 149267-24-3
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CGP 53820 is an inhibitor for HIV protease, inhibits the complex of HIV-1 and HIV-2 protease with Ki of 9 and 53 nM for HIV-1 protease and HIV-2 protease. CGP 53820 can be used in AIDS research .
Cat. No.: HY-146089
CAS No.: 1033950-94-5
HIV-1 inhibitor-32 (compound 3c) is a potent HIV-1 inhibitor with an IC50 value of 34 nM for WT HIV-1. HIV-1 inhibitor-32 can be used for researching AIDS .
Cat. No.: HY-147370
CAS No.: 332947-35-0
HIV-1 inhibitor-46 (compound 13d) is a potent HIV-1 non-nucleoside reverse transcriptase inhibitor with an EC50 value of 1.425 μM. HIV-1 inhibitor-46 can be used for the research of AIDS .
Cat. No.: HY-146090
CAS No.: 2395777-43-0
HIV-1 inhibitor-33 (compound 5n) is a potent and selective HIV-1 inhibitor with an EC50 of 8.6 nM for HIV-1 and a CC50 of 18 μM in MT-4 cells. HIV-1 inhibitor-33 can be used for researching AIDS .
Cat. No.: HY-146091
CAS No.: 2395777-45-2
HIV-1 inhibitor-34 (compound 5q) is a potent and selective HIV-1 inhibitor with an EC50 of 6.4 nM for HIV-1 and a CC50 of 16 μM in MT-4 cells. HIV-1 inhibitor-34 can be used for researching AIDS .
Cat. No.: HY-160634
CAS No.: 1446233-35-7
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BRD4 Inhibitor-31 (Example 136) is a BRD4 inhibitor (Kis: 0.234 μM and 0.295 μM for BRD4 BD1 and BRD4 BD2 respectively). BRD4 Inhibitor-31 can be used for research of inflammatory diseases, cancer, and AIDS .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
