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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
172 Results for "
AIDs
" in MedChemExpress (MCE) Product Catalog:
Products (172)
172 Results for "AIDs" in MCE Product Catalog:
Cat. No.: HY-136548
CAS No.: 166403-66-3
Synonyms: TFV-DP
Target:
Research Areas:
Tenofovir diphosphate is an antiretroviral agent. Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase DNA (Ki = 1.55 μM) and RNA (Ki = 0.022 μM). Tenofovir diphosphate can be used for the research of AIDS .
Category:
Infection Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
Megestrol is an orally active glucocorticoid and progesterone receptor agonist. Megestrol can alleviate anorexia, cachexia or unexplained significant weight loss associated with acquired immunodeficiency syndrome (AIDS). Megestrol may cause manifestations similar to those of glucocorticoids and increase the risk of mental disorders .
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Metabolic Disease
Moxisylyte (Thymoxamine) hydrochloride is a selective α1A-adrenergic receptor antagonist. Moxisylyte hydrochloride competitively antagonizes the activation mediated by norepinephrine. Moxisylyte hydrochloride relaxes penile cavernous smooth muscle and aids erectile function. Moxisylyte hydrochloride is applicable to research related to erectile dysfunction and multiple system atrophy .
Synonyms: BW 301U; NSC 351521
Target:
Piritrexim (BW 301U) is a potent dihydrofolate reductase (DHFR) inhibitor against Pneumocystis carinii and Toxoplasma gondii, with IC50 values of 0.038 and 0.011 μM, respectively. Piritrexim can be used for acquired immune deficiency syndrome (AIDS) research. Piritrexim also is an anticancer agent .
Cat. No.: HY-N0685
CAS No.: 55954-61-5
Category:
Infection Quinones Anthraquinones Guttiferae Hyperlcurn perforatum L. Phenols Polyphenols Plants Disease Research Fields
Target:
Cat. No.: HY-10570R
CAS No.: 129618-40-2
Synonyms: BI-RG 587 (Standard); NSC 641530 (Standard); NVP (Standard)
Nevirapine (Standard) is the analytical standard of Nevirapine. This product is intended for research and analytical applications. Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase used to treat and prevent HIV/AIDS; with a Ki of 270 μM .
Cat. No.: HY-90001S
CAS No.: 1616968-73-0
Synonyms: ABT 538-d6; RTV-d6
Target:
Research Areas:
Bamethan (DL-Bamethane) hemisulfate is a vasodilator that exhibits significant activity in enhancing blood flow and reducing vascular resistance. Bamethan hemisulfate plays a crucial role in the treatment of cardiovascular conditions by improving oxygen delivery to tissues. Bamethan hemisulfate also aids in the management of hypertension through its relaxing effects on blood vessels.
Cat. No.: HY-162836
CAS No.: 13929-35-6
Synonyms: 4-O-(Carboxymethyl)-Rifamycin
Target:
Research Areas:
Rifamycin B (4-O-(Carboxymethyl)-Rifamycin) is a member of ansamycin antibiotics family with an anti-mycobacterial activity against tuberculosis, leprosy and AIDS-related mycobacterial infections. Rifamycin B is a metabolic product of Nocardia inediterranei, which can yield Rifamycin O and Rifamycin S (HY-125365) by microbial transformation .
Cat. No.: HY-145569A
CAS No.: 2442512-14-1
Synonyms: GSK3640254 dihydrochloride
Fipravirimat dihydrochloride is a potent HIV-1 inhibitor. Fipravirimat dihydrochloride has the potential for HIV and AIDS research .
Cat. No.: HY-P10358
CAS No.: 1505463-57-9
Target:
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Hydroxy ritonavir is a metabolite of Ritonavir. Ritonavir is an inhibitor of HIV protease used to treat HIV infection and AIDS .
Cat. No.: HY-W115757
CAS No.: 14987-04-3
Cat. No.: HY-W016664
CAS No.: 461-82-5
Research Areas:
4-(Trifluoromethoxy) aniline is an intermediate. 4-(Trifluoromethoxy) aniline can be used for the synthesis of Compound 80. 4-(Trifluoromethoxy) aniline can be applied to AIDS research .
Cat. No.: HY-106920
CAS No.: 147318-81-8
Synonyms: KNI 272; Kynostatin; NSC 651714
Target:
Research Areas:
Kynostatin 272 (KNI 272) is a potent HIV protease inhibitor. Kynostatin 272 inhibits the activity of the HIV protease by simulating the substrate transition state of the HIV protease, thus preventing a key step in the replication of the HIV virus. Kynostatin 272 provides an important research foundation for the development of drugs for HIV and AIDS .
Cat. No.: HY-123330
CAS No.: 457635-65-3
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Research Areas:
GW695634 is an orally active prodrug of GW678248. GW695634 undergoes amidolysis in vivo to release the active ingredient GW678248, thereby inhibiting viral replication. GW678248 is a non-nucleoside reverse transcriptase inhibitor (NNRTi) with potent antiviral activity against Efavirenz (HY-10572)-resistant and Nevirapine (HY-10570)-resistant HIV and AIDS viruses .
Cat. No.: HY-146353
CAS No.: 2642217-95-4
Target:
Research Areas:
HIV-1 inhibitor-29 (compound 14d2) is a potent HIV-1 inhibitor with an EC50 of 2.18 μM for HIV-1 IIIB. HIV-1 inhibitor-29 has high anti-resistance profile toward F227L/V106A strain (EC50 = 0.974 μM), and exhibits low cytotoxicity in MT-4 cells (CC50 = 211 μM). HIV-1 inhibitor-29 can be used for researching AIDS .
Cat. No.: HY-15592R
CAS No.: 1051375-10-0
Synonyms: GSK-1265744 (Standard); S/GSK1265744 (Standard)
Target:
Research Areas:
Cabotegravir (Standard) is the analytical standard of Cabotegravir. This product is intended for research and analytical applications. Cabotegravir (GSK-1265744) is a orally active and long-acting HIV integrase strand transfer inhibitor and organic anion transporter 1/3 (OAT1/OAT3) inhibitor with IC50 values of 2.5 nM, 0.41 μM and 0.81 μM for HIVADA, OAT3 and OAT1, respectively. Cabotegravir is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1, with low potential to interact with other antiretroviral agents (ARVs). Cabotegravir can be used to research AIDS .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
