72732-56-0
72732-56-0
Chemical Structure
Piritrexim
Synonym(s): BW 301U; NSC 351521
- CAS No.: 72732-56-0
- Formula:C17H19N5O2
- Molecular Weight:325.37
IUPAC Name: 6-(2,5-dimethoxybenzyl)-5-methylpyrido[2,3-d]pyrimidine-2,4-diamine
InChIKey: VJXSSYDSOJBUAV-UHFFFAOYSA-N
SMILES: CC1=C(CC2=C(C=CC(OC)=C2)OC)C=NC3=NC(N)=NC(N)=C13
Biological Activity: Piritrexim (BW 301U) is a potent dihydrofolate reductase (DHFR) inhibitor against Pneumocystis carinii and Toxoplasma gondii, with IC50 values of 0.038 and 0.011 μM, respectively. Piritrexim can be used for acquired immune deficiency syndrome (AIDS) research. Piritrexim also is an anticancer agent[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Piritrexim | 99.07% | Piritrexim (BW 301U) is a potent dihydrofolate reductase (DHFR) inhibitor against Pneumocystis carinii and Toxoplasma gondii, with IC50 values of 0.038 and 0.011 μM, respectively. Piritrexim can be used for acquired immune deficiency syndrome (AIDS) research. Piritrexim also is an anticancer agent. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.86
HY-167863Piritrexim isethionate -
Similarity Score 0.63
HY-121466Ormetoprim -
Similarity Score 0.63
HY-B1902Diaveridine -
Similarity Score 0.60
HY-19978RO-3 -
Similarity Score 0.60
HY-177337N-Didesmethyladitoprim -
Similarity Score 0.60
HY-W5876634′-DTMP -
Similarity Score 0.60
HY-121341RBrodimoprim (Standard) -
Similarity Score 0.60
HY-B0510Trimethoprim -
Similarity Score 0.60
HY-B0510S3Trimethoprim-13C3 -
Explore the MedChemAI to find more analogs
