HIV-1 inhibitor-32
HIV-1 inhibitor-32 (compound 3c) is a potent HIV-1 inhibitor with an IC50 value of 34 nM for WT HIV-1. HIV-1 inhibitor-32 can be used for researching AIDS.
For research use only. We do not sell to patients.
- CAS No.: 1033950-94-5
- Formula: C26H29N5O3S
- Molecular Weight:491.61
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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HIV-1 (WT) 34 nM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MT4 | IC50 |
0.3 nM
Compound: 5h
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Antiviral activity against HIV1 infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect
Antiviral activity against HIV1 infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect
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[PMID: 20538456] |
| MT4 | IC50 |
16.9 nM
Compound: 5h
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Antiviral activity against HIV1 expressing reverse transcriptase Y188L mutant infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect
Antiviral activity against HIV1 expressing reverse transcriptase Y188L mutant infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect
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[PMID: 20538456] |
| MT4 | IC50 |
20.2 nM
Compound: 5h
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Antiviral activity against HIV1 expressing reverse transcriptase K103N/Y181C double mutant infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect
Antiviral activity against HIV1 expressing reverse transcriptase K103N/Y181C double mutant infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect
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[PMID: 20538456] |
Chemical Information
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CAS No. 1033950-94-5
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Molecular Weight 491.61
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Formula C26H29N5O3S
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SMILES
N#CC1=CC(C)=C(OC2=NC(NC3CCN(CC4=CC=C(S(=O)(C)=O)C=C4)CC3)=NC=C2)C(C)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HIV-1 inhibitor-32 Related Classifications
HY-146089 Related Classifications
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