NNRT-IN-9
NNRT-IN-9 (Compound EG28) is a non-nucleoside reverse transcriptase (NNRT) inhibitor. NNRT-IN-9 has potent antiviral and anti-resistance activity against wild-type (WT) HIV-1 and various clinically relevant mutations (E138K and K103N + Y181C) with EC50s of 55, 67 and 3910 nM, respectively. NNRT-IN-9 can be used for acquired immune deficiency syndrome (AIDS) research.
For research use only. We do not sell to patients.
- Formula: C22H16N6O
- Molecular Weight:380.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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HIV-1 (WT) 55 nM (EC50) |
HIV-1 (E138K) 67 nM (EC50) |
HIV-1 (K103N+Y181C) 3910 nM (EC50) |
Chemical Information
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Molecular Weight 380.40
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Formula C22H16N6O
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SMILES
N#CC1=CC(N2C(N(CC3=CC=CC=C32)CC4=NNC5=NC=CC=C45)=O)=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)