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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
268 Results for "
BMP
" in MedChemExpress (MCE) Product Catalog:
Products (268)
268 Results for "BMP" in MCE Product Catalog:
1
1 Cited Publications
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LP-922761 is a potent, selective and orally active adapter protein-2 associated kinase 1 (AAK1) inhibitor with IC50s of 4.8 nM and 7.6 nM in enzyme and cell assays, respectively. LP-922761 also inhibits BMP-2-inducible protein kinase (BIKE) with an IC50 of 24 nM. LP-922761 exhibits no significant activity at cyclin G-associated kinase (GAK), opioid, adrenergic α2 or GABAa receptors .
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DMH2 is a potent BMP receptor antagonist. DMH2 downregulates the expression of Id1 and Id3 proteins, and inhibits the proliferation and induces cell death of lung cancer cell lines .
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1 Cited Publications
Cat. No.: HY-P700021AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GDF7; Growth/Differentiation Factor 7; Growth Differentiation Factor 7; GDF-7; BMP12
Species:
Human
Source:
E. coli
1
1 Cited Publications
SGC-AAK1-1, a chemical probe, is a potent and selective AAK1 (AP2 associated kinase 1) inhibitor with an IC50 of 270 nM and a Ki of 9 nM. SGC-AAK1-1 also potently inhibits BMP2K. SGC-AAK1-1 is used to study Wnt pathway related to AAK1 .
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1
1 Cited Publications
Cat. No.: HY-P7822
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CER1; DAN Domain Family Member 4; Cerberus 1, DAN Family BMP Antagonist; Cerberus 1 (Xenopus Laevis) Homolog (Cysteine Knot Superfamily); DAND4; Cerberus 1, Cysteine Knot Superfamily, Homolog (Xenopus Laevis); Cerberus-Related Protein; Cerberus 1, Cystein
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-N0559
CAS No.: 52659-56-0
Category:
Terpenoids Bituminaria morisiana (Pignatti & Metlesics) Greuter Diterpenoids Plants Compositae
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Cat. No.: HY-42146
CAS No.: 55750-62-4
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BMPS is a nonclaevable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Cat. No.: HY-P5832
CAS No.: 836606-84-9
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Cat. No.: HY-P10710
CAS No.: 1629625-47-3
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BMP agonist 2 (derivative I-9) is a potent bone-inducing cytokine. BMP agonist 2 promotes bone tissue production by increasing the proportion and activity of osteoblasts. BMP agonist 2 promotes osteoblast proliferation and differentiation through the BMP2-ATF4 signaling axis, in which ATF4 is a transcription factor closely related to osteoblast differentiation and bone formation. BMP agonist 2 can be used in the study of senile osteoporosis (SOP) .
Cat. No.: HY-155705
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BMP agonist 1 (compound 2 b) is a small-molecule agonist of bone morphogenic protein (BMP). BMP induces C2C12 cell differentiation with BMP and highly depends on active BMP signaling. BMP agonist 1 inhibits GSK3β, increases β-catenin signaling and synergistically regulates Id2and Id3 expression. BMP agonist 1 is used in diseases and defects of the skeleton research .
Cat. No.: HY-201672
CAS No.: 799268-67-0
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Cat. No.: HY-P5457
CAS No.: 500719-13-1
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Cat. No.: HY-RS01533
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BMP1 Human Pre-designed siRNA Set A contains three designed siRNAs for BMP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17130
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Bmp2k Mouse Pre-designed siRNA Set A contains three designed siRNAs for Bmp2k gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS01534
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BMP10 Human Pre-designed siRNA Set A contains three designed siRNAs for BMP10 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS01535
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BMP15 Human Pre-designed siRNA Set A contains three designed siRNAs for BMP15 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS01536
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BMP2 Human Pre-designed siRNA Set A contains three designed siRNAs for BMP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS01538
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BMP3 Human Pre-designed siRNA Set A contains three designed siRNAs for BMP3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
