2247894-32-0
2247894-32-0
Chemical Structure
SGC-AAK1-1
- CAS No.: 2247894-32-0
- Formula:C21H25N5O3S
- Molecular Weight:427.52
IUPAC Name: N-(6-(3-((N,N-diethylsulfamoyl)amino)phenyl)-1H-indazol-3-yl)cyclopropanecarboxamide
InChIKey: UCBIQZUJJSVQHL-UHFFFAOYSA-N
SMILES: O=C(C1CC1)NC2=NNC3=C2C=CC(C4=CC=CC(NS(=O)(N(CC)CC)=O)=C4)=C3
Biological Activity: SGC-AAK1-1, a chemical probe, is a potent and selective AAK1 (AP2 associated kinase 1) inhibitor with an IC50 of 270 nM and a Ki of 9 nM. SGC-AAK1-1 also potently inhibits BMP2K. SGC-AAK1-1 is used to study Wnt pathway related to AAK1[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
SGC-AAK1-1 | 98.47% | SGC-AAK1-1, a chemical probe, is a potent and selective AAK1 (AP2 associated kinase 1) inhibitor with an IC50 of 270 nM and a Ki of 9 nM. SGC-AAK1-1 also potently inhibits BMP2K. SGC-AAK1-1 is used to study Wnt pathway related to AAK1. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
