190 Results for "

Sedative

" in MedChemExpress (MCE) Product Catalog:
Products (190)

190 Results for "Sedative" in MCE Product Catalog:

Cat. No.: HY-116195
CAS No.: 126-91-0
Purity:  ≥98.0%
Synonyms: (-)-Linalool
L-Linalool, a monoterpene with sedative and anxiolytic potential, has been used in Parkinson's disease research .
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Cat. No.: HY-Y0121R
CAS No.: 103-36-6
Ethyl cinnamate (Standard) is the analytical standard of Ethyl cinnamate. This product is intended for research and analytical applications. Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga, exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC50 values of 0.30 mM and 0.38 mM in rat aorta .
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Cat. No.: HY-W707158
CAS No.: 673-18-7
Synonyms: (±)-Norfenfluramine hydrochloride
Norfenfluramine hydrochloride ((±)-Norfenfluramine hydrochloride) is a major and brain-penetrant metabolite of Fenfluramine. Norfenfluramine hydrochloride can interact with 5-HT transporters to release 5-HT from neurons. Norfenfluramine hydrochloride displays antiepileptic effects in vivo .
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Cat. No.: HY-N16466
CAS No.: 4176-16-3
Synonyms: Nardal
Valerenal (Nardal) is a sesquiterpene found in Valeriana officinalis root oil. Valerian root can be used as an herbal sedative which is helpful in the treatment of insomnia .
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Cat. No.: HY-16505
CAS No.: 7246-20-0
Target:  

Endogenous Metabolite

Research Areas:  

Neurological Disease

Triclofos sodium is a drug used to suppress insomnia and for sedation and has sedative activity. Triclofos sodium is used in children for sedation during painless medical procedures, particularly in children with neurocognitive disorders. Triclofos sodium has similar physiological and pharmacological properties to chloral and therefore can be used as a substitute when necessary. The safety and efficacy of Triclofos sodium have been demonstrated in pediatric populations with high rates of neurocognitive disorders .
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Cat. No.: HY-17034BR
CAS No.: 86347-15-1
Synonyms: MPV785 (Standard)
Medetomidine (hydrochloride) (Standard) is the analytical standard of Medetomidine (hydrochloride). This product is intended for research and analytical applications. Medetomidine hydrochloride is an orally active α2-adrenoceptor agonist (Ki: 1.08 nM). Medetomidine hydrochloride has sedative and analgesic effects. Medetomidine hydrochloride can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels .
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Cat. No.: HY-N11706
CAS No.: 546-28-1
Synonyms: (+)-β-Cedrene
β-Cedrene ((+)-β-Cedrene) is a sesquiterpene compound that can be isolated from Centaurea kotschyi var. kotschyi and Centaurea kotschyi var. decumbens, exhibiting antibacterial, anti-inflammatory, antispasmodic, tonic, diuretic, sedative, insecticidal, and antifungal activities. β-Cedrene is also a potent competitive inhibitor of the CYP2B6-mediatedbupropion hydroxylase, with a Ki value of 1.6 μM .
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Cat. No.: HY-N2081R
CAS No.: 83-95-4
Skimmianine (Standard) is the analytical standard of Skimmianine. This product is intended for research and analytical applications. Skimmianine is an orally active furoquiniline alkaloid present mainly in the Rutaceae family. Skimmianine has analgesic, antispastic, sedative, and anti-inflammatory properties. Skimmianine inhibits acetylcholinesterase (AChE) (IC50 = 8.6 μg/mL). Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity. Skimmianine has antioxidant and anti-inflammatory effects on ischemia-reperfusion (IR) injury. Skimmianine exerts anti-inflammatory effects through activation of the phosphatidylinositol-3-kinase (PI3K)-protein kinase B (AKT) pathway. Skimmianine is neuroprotective by targeting the NF-κB activation pathway to prevent neuroinflammation. Skimmianine inhibits the release of histamine, intracellular Ca 2+ signaling and protein kinase C signaling .
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Cat. No.: HY-B1594
CAS No.: 77-65-6
Synonyms: Adalin; Adisomnol; Bromacetocarbamide
Target:  

Others

Research Areas:  

Neurological Disease

Carbromal (Adalin; Adisomnol) is a sedative with centrally depressant effects .
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Cat. No.: HY-14785A
CAS No.: 2436760-81-3
Purity:  99.93%
Synonyms: NLX-112 hydrochloride; F 13640 hydrochloride
Target:  

5-HT Receptor

Befiradol (NLX-112) hydrochloride is a highly selective 5-HT1A receptor agonist that acts on both presynaptic and postsynaptic sites. Befiradol hydrochloride attenuates sedative agent-induced respiratory depression in neonatal and adult rats. Befiradol reduces the duration of sedative agent-induced analgesia and sedation in adult rats. Befiradol hydrochloride can be used in studies related to opioid-induced respiratory depression .
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Cat. No.: HY-B0163
CAS No.: 76631-46-4
Detomidine, an imidazole derivative, is a potent α2-adrenergic agonist. Detomidine produces dose-dependent analgesic effects .
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Cat. No.: HY-100377
CAS No.: 82351-05-1
Purity:  99.48%
Synonyms: Anticonvulsant 7903
Target:  

Others

Research Areas:  

Neurological Disease

Lvguidingan is a potent anticonvulsant agent. Lvguidingan also has sedative-hypnotic, tranquilizing, and muscle-relaxing actions. Lvguidingan can be used as antiepileptic agent .
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Cat. No.: HY-W660701
CAS No.: 4945-47-5
Bamipine is a potent histamine H1-receptor antagonist. Bamipine exhibits moderate activity against Mycobacterium tuberculosis. Bamipine has a mild sedative effect .
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Cat. No.: HY-W740244
CAS No.: 53818-10-3
Target:  

OAT

Research Areas:  

Metabolic Disease

4’-hydroxy Trazodone is a metabolite of the antidepressant and sedative trazodone. It is an inhibitor of organic anion transporter 3 (OAT3; Ki=16.9 μM) and is selective for OAT3 over OAT1 (Ki=>200 μM).
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Cat. No.: HY-121890
CAS No.: 66857-17-8
Target:  

Others

Research Areas:  

Neurological Disease

Etoxybamide is a sedative. Etoxybamide has sedative and hypnotic effects .
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Cat. No.: HY-B1504
CAS No.: 77-66-7
Synonyms: Acetylcarbromal
Target:  

Drug Derivative

Research Areas:  

Neurological Disease

Acecarbromal (Acetylcarbromal) is a Urea (HY-Y0271) derivative. Acecarbromal is a hypnotic and sedative agent .
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Cat. No.: HY-122169
CAS No.: 36292-69-0
Synonyms: Ketocyclazocine
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

Ketazocine (Ketocyclazocine) is a selective κ-opioid receptor (KOR) agonist. Ketazocine is promising for research of analgesics and sedatives .
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Cat. No.: HY-105481
CAS No.: 102200-24-8
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

CGS-17867A hydrochloride is a benzodiazepine receptor ligand. CGS-17867A hydrochloride has a weak sedative effect and can increase palatable food intake .
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Cat. No.: HY-167650
CAS No.: 34482-99-0
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

Fletazepam is a benzodiazepine derivative with sedative, anxiolytic and muscle relaxant effects. Fletazepam can be utilized in neurological research .
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Cat. No.: HY-125508
CAS No.: 162883-07-0
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

CCD-3693 is an orally active GABA receptor agonist. CCD-3693 has anxiolytic, anticonvulsant and sedative hypnotic activities and can be used in research related to neurological diseases .
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