53818-10-3
53818-10-3
Chemical Structure
4’-Hydroxy Trazodone
- CAS 番号: 53818-10-3
- Formula:
- Molecular Weight:387.86
IUPAC Name: 2-(3-(4-(3-chloro-4-hydroxyphenyl)piperazin-1-yl)propyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
InChIKey: FNUZSRSXQFIOPL-UHFFFAOYSA-N
SMILES: ClC1=CC(N2CCN(CCCN3N=C(C=CC=C4)N4C3=O)CC2)=CC=C1O
Biological Activity: 4’-hydroxy Trazodone is a metabolite of the antidepressant and sedative trazodone. It is an inhibitor of organic anion transporter 3 (OAT3; Ki=16.9 μM) and is selective for OAT3 over OAT1 (Ki=>200 μM).
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4’-Hydroxy Trazodone | 4’-hydroxy Trazodone is a metabolite of the antidepressant and sedative trazodone. It is an inhibitor of organic anion transporter 3 (OAT3; Ki=16.9 μM) and is selective for OAT3 over OAT1 (Ki=>200 μM). | |||||||||||||||||||||
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Keywords
