86347-15-1
86347-15-1
Chemical Structure
Medetomidine hydrochloride
Synonym(s): MPV785
- CAS No.: 86347-15-1
- Formula:C13H17ClN2
- Molecular Weight:236.74
IUPAC Name: 5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole hydrochloride
InChIKey: VPNGEIHDPSLNMU-UHFFFAOYSA-N
SMILES: CC(C1=CN=CN1)C2=CC=CC(C)=C2C.Cl
Biological Activity: Medetomidine hydrochloride is an orally active α2-adrenoceptor agonist (Ki: 1.08 nM). Medetomidine hydrochloride has sedative and analgesic effects. Medetomidine hydrochloride can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels[1][2][3][4].
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Medetomidine hydrochloride | 99.94% | Medetomidine hydrochloride is an orally active α2-adrenoceptor agonist (Ki: 1.08 nM). Medetomidine hydrochloride has sedative and analgesic effects. Medetomidine hydrochloride can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels. | ||||||||||||||||||||
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Medetomidine hydrochloride (Standard) | ≥98% | Medetomidine (hydrochloride) (Standard) is the analytical standard of Medetomidine (hydrochloride). This product is intended for research and analytical applications. Medetomidine hydrochloride is an orally active α2-adrenoceptor agonist (Ki: 1.08 nM). Medetomidine hydrochloride has sedative and analgesic effects. Medetomidine hydrochloride can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels. | ||||||||||||||||||||
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Medetomidine-13C,d3 hydrochloride | 99.48% | Medetomidine-13C,d3 (hydrochloride) is a deuterated labeled Medetomidine (hydrochloride). Medetomidine hydrochloride is an orally active α2-adrenoceptor agonist (Ki: 1.08 nM). Medetomidine hydrochloride has sedative and analgesic effects. Medetomidine hydrochloride can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels. | ||||||||||||||||||||
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Medetomidine-d3 hydrochloride | Medetomidine-d3 (hydrochloride) is the deuterium labeled Medetomidine hydrochloride. Medetomidine hydrochloride is an agonist of adrenergic alpha-2 receptor. | |||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Kallio A, et al. Acute effects of medetomidine, a selective alpha 2-adrenoceptor agonist, on anterior pituitary hormone and cortisol secretion in man. Acta Endocrinol (Copenh). 1988 Sep;119(1):11-5. [Content Brief]
- [3]. R Virtanen, et al. Characterization of the selectivity, specificity and potency of medetomidine as an a2-adrenoceptor agonist. [Content Brief]
- [4]. O. B. Ansah, et al. Comparing oral and intramuscular administration of medetomidine in cats.
