4945-47-5
4945-47-5
Chemical Structure
Bamipine
- CAS No.: 4945-47-5
- Formula:C19H24N2
- Molecular Weight:280.41
IUPAC Name: N-benzyl-1-methyl-N-phenylpiperidin-4-amine
InChIKey: VZSXTYKGYWISGQ-UHFFFAOYSA-N
SMILES: CN1CCC(CC1)N(CC1=CC=CC=C1)C1=CC=CC=C1
Biological Activity: Bamipine is a potent histamine H1-receptor antagonist. Bamipine exhibits moderate activity against Mycobacterium tuberculosis. Bamipine has a mild sedative effect[1][2].
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Bamipine | Bamipine is a potent histamine H1-receptor antagonist. Bamipine exhibits moderate activity against Mycobacterium tuberculosis. Bamipine has a mild sedative effect. | |||||||||||||||||||||
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References
- [1]. Weis R, et al. Antimycobacterial and H1-antihistaminic activity of 2-substituted piperidine derivatives. Bioorg Med Chem. 2008 Dec 15;16(24):10326-31. [Content Brief]
- [2]. Kountourelli JE, Markopoulou CK. A simultaneous analysis by high performance liquid chromatography of bamipine combined with tricyclic antidepressants and/or antipsychotics in dosage forms. Journal of liquid chromatography. 1991 Sep 1;14(15):2969-77.
