2436760-81-3
Chemical Structure
Befiradol hydrochloride
Synonym(s): NLX-112 hydrochloride; F 13640 hydrochloride
- CAS No.: 2436760-81-3
- Formula:C20H23Cl2F2N3O
- Molecular Weight:430.32
IUPAC Name: (3-chloro-4-fluorophenyl)(4-fluoro-4-((((5-methylpyridin-2-yl)methyl)amino)methyl)piperidin-1-yl)methanone hydrochloride
InChIKey: MEFWJLIGVNWMAB-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(F)C(Cl)=C1)N2CCC(CNCC3=NC=C(C)C=C3)(F)CC2.Cl
Biological Activity: Befiradol (NLX-112) hydrochloride is a highly selective 5-HT1A receptor agonist that acts on both presynaptic and postsynaptic sites. Befiradol hydrochloride attenuates sedative agent-induced respiratory depression in neonatal and adult rats. Befiradol reduces the duration of sedative agent-induced analgesia and sedation in adult rats. Befiradol hydrochloride can be used in studies related to opioid-induced respiratory depression[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Befiradol hydrochloride | 98.80% | Befiradol (NLX-112) hydrochloride is a highly selective 5-HT1A receptor agonist that acts on both presynaptic and postsynaptic sites. Befiradol hydrochloride attenuates sedative agent-induced respiratory depression in neonatal and adult rats. Befiradol reduces the duration of sedative agent-induced analgesia and sedation in adult rats. Befiradol hydrochloride can be used in studies related to opioid-induced respiratory depression. | ||||||||||||||||||||
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Similarity Score 0.98
HY-14785Befiradol -
Similarity Score 0.81
HY-19863F-15599 -
Similarity Score 0.81
HY-146232F 13714 -
Similarity Score 0.72
HY-128901F 13714 fumarate -
Similarity Score 0.70
HY-182389NLX-219 -
Similarity Score 0.70
HY-172924NLX-266 -
Similarity Score 0.68
HY-19863AF-15599 tosylate -
Similarity Score 0.50
HY-133735AGRP-60367 hydrochloride -
Similarity Score 0.49
HY-U00459BGSK2850163 hydrochloride -
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