2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. Befiradol

Befiradol  (Synonyms: NLX-112; F13640)

Cat. No.: HY-14785 Purity: 99.20%
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Befiradol (NLX-112) is a selective 5-HT1A receptor agonist.

For research use only. We do not sell to patients.

Befiradol Chemical Structure

Befiradol Chemical Structure

CAS No. : 208110-64-9

Size Price Stock Quantity
5 mg USD 110 In-stock
10 mg USD 180 In-stock
25 mg USD 380 In-stock
50 mg USD 610 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Befiradol:

Befiradol Related Antibodies

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Description

Befiradol (NLX-112) is a selective 5-HT1A receptor agonist.

IC50 & Target

5-HT1A Receptor

 

Clinical Trial
Molecular Weight

393.86

Formula

C20H22ClF2N3O
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC=C(F)C(Cl)=C1)N2CCC(CNCC3=NC=C(C)C=C3)(F)CC2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 102 mg/mL (258.98 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5390 mL 12.6949 mL 25.3897 mL
5 mM 0.5078 mL 2.5390 mL 5.0779 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5390 mL 12.6949 mL 25.3897 mL 63.4743 mL
5 mM 0.5078 mL 2.5390 mL 5.0779 mL 12.6949 mL
10 mM 0.2539 mL 1.2695 mL 2.5390 mL 6.3474 mL
15 mM 0.1693 mL 0.8463 mL 1.6926 mL 4.2316 mL
20 mM 0.1269 mL 0.6347 mL 1.2695 mL 3.1737 mL
25 mM 0.1016 mL 0.5078 mL 1.0156 mL 2.5390 mL
30 mM 0.0846 mL 0.4232 mL 0.8463 mL 2.1158 mL
40 mM 0.0635 mL 0.3174 mL 0.6347 mL 1.5869 mL
50 mM 0.0508 mL 0.2539 mL 0.5078 mL 1.2695 mL
60 mM 0.0423 mL 0.2116 mL 0.4232 mL 1.0579 mL
80 mM 0.0317 mL 0.1587 mL 0.3174 mL 0.7934 mL
100 mM 0.0254 mL 0.1269 mL 0.2539 mL 0.6347 mL
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Befiradol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Befiradol208110-64-9NLX-112 F13640NLX112NLX 112F13640F 13640F-136405-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorInhibitorinhibitorinhibit

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