61 Results for "

TSLP

" in MedChemExpress (MCE) Product Catalog:
Products (61)

61 Results for "TSLP" in MCE Product Catalog:

Cat. No.: HY-P700601
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Thymic Stroma-Derived Lymphopoietin; Thymic Stromal Lymphopoietin; TSLP
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P78225
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Thymic Stroma-Derived Lymphopoietin; Thymic Stromal Lymphopoietin; TSLP
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P78658
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Thymic Stroma-Derived Lymphopoietin; Thymic Stromal Lymphopoietin; TSLP
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P78659
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Thymic Stroma-Derived Lymphopoietin; Thymic Stromal Lymphopoietin; TSLP
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704948
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Thymic Stroma-Derived Lymphopoietin; Thymic Stromal Lymphopoietin; TSLP
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P992447

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

QX008N is a humanized IgG1 monoclonal antibody and also a TSLP inhibitor with a KD value of 0.0175 nM. QX008N blocks TSLP-induced signaling pathways by inhibiting the interaction of TSLP-TSLPR-IL-7Rα. QX008N reduces eosinophil and IgE levels, improves pulmonary function, blocks TSLP-induced inflammation, and enhances the inhibitory effect on inflammatory mediators when administered in combination with anti-IL-4R antibodies. QX008N is applicable to relevant research on asthma .
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Cat. No.: HY-P992378

Target:  

CCR STAT

Research Areas:  

Inflammation/Immunology Cancer

HZ-1127 is a thymic stromal lymphopoietin (TSLP) inhibitor. HZ-1127 selectively binds to TSLP, blocks receptor complex interaction, inhibits STAT5 activation, downstream inflammatory signaling, and TSLP-induced CCL17 and CCL22 secretion. HZ-1127 can be used for the research of allergic diseases and cancer .
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Cat. No.: HY-P992452

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

RO-5469754 is a humanized monoclonal antibody that specifically binds to human thymic stromal lymphopoietin (TSLP). RO-5469754 blocks the binding of hTSLP to its receptor complex, thereby neutralizing TSLP-mediated biological activities, and does not cross-react with TSLP from cynomolgus monkeys or mice. RO-5469754 can be further used to generate the bispecific antibody TAVO101 × IL4R-dupi .
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Cat. No.: HY-P992359
Synonyms: SHR-1905

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

GSK5784283 (SHR-1905) is a bivalent antibody against TSLP, which is applicable to research related to asthma. GSK5784283 has two Fab arms and is a humanized IgG1κ monoclonal antibody. GSK5784283 effectively reduces the levels of eosinophils, FeNO, TARC and eotaxin-3. GSK5784283 regulates FEV1 (forced expiratory volume in one second) .
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Cat. No.: HY-206870
CAS No.: 3104965-33-2
Research Areas:  

Inflammation/Immunology

BP79 is a potent TSLP receptor inhibitor. BP79 disrupts TSLP-mediated ternary complex formation, blocks TSLPR-IL7Rα co-localization, binds and stabilizes TSLPR, and inhibits phosphorylated STAT3/6. BP79 suppresses immune cell infiltration, secretion of IL-13, IL-4. BP79 can be used for the research of inflammation diseases, such as atopic dermatitis, allergic asthma, and allergic rhinitis .
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Cat. No.: HY-P811326
Synonyms: Thymic stromal lymphopoietin, Thymic stroma-derived lymphopoietin, TSLP

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-404647
CAS No.: 560111-91-3
FK3453 is a dual adenosine A1/A2 inhibitor and a TSLP inhibitor. FK3453 is also a substrate of aldehyde oxidase (AO). FK3453 can inhibit the production of TSLP and IL-33. FK3453 is useful for research on Parkinson’s disease and allergic disorders .
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Cat. No.: HY-182362
Research Areas:  

Inflammation/Immunology

TK-285 is a potent TSLP inhibitor that suppresses the production of TSLP and inhibits the expression of interleukin-33 mRNA. TK-285 exhibits a selective binding preference for the BD1 domains of BRD2, BRD3, BRD4 and BRDT. TK-285 can be used in research related to atopic dermatitis .
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Cat. No.: HY-P70794
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CRLF2; IL-XR; Cytokine Receptor Like Factor 2; Thymic Stromal-Derived Lymphopoietin Receptor; TSLPR; Cytokine Receptor CRL2 Precusor; CRL2; Cytokine Receptor-Like 2; Thymic Stromal Lymphopoietin Protein Receptor; CRLF2Y; Cytokine Receptor-Like Factor 2; P2RY8; TSLP Receptor; ILXR
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P992474
TAVO101 is a humanized anti-TSLP antibody with an EC50 of 0.19 nM against hTSLP. TAVO101 inhibits STAT5 activation and CCL17 release. TAVO101 carries Fc region mutations that enhance its binding to FcRn while reducing its binding to FcγRI, FcγRIIIA and C1q, thereby attenuating effector functions. TAVO101 reduces the levels of inflammatory markers, cell infiltration and histopathological damage in preclinical models of asthma, psoriasis and atopic dermatitis. TAVO101 can be used for research related to asthma, psoriasis and atopic dermatitis .
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Cat. No.: HY-181576
CAS No.: 3115784-59-0
Target:  

ROCK

Research Areas:  

Inflammation/Immunology

ROCK2-IN-14 is an orally active, selective ROCK2 inhibitor (IC50=4.8 nM) with 212-fold selectivity over ROCK1 (IC50=1.01 μM). By inhibiting the ROCK2/S100A9 signaling pathway, ROCK2-IN-14 downregulates S100A9 expression, inhibits NM2 phosphorylation and restores cytoskeletal abnormalities. Furthermore, ROCK2-IN-14 reduces inflammatory cytokine levels, alleviates skin inflammation and exerts anti-inflammatory activity. ROCK2-IN-14 also significantly inhibits ear thickening in a mouse model of atopic dermatitis (AD), and decreases the levels of IgE, TNF-α, IL-6 and TSLP. ROCK2-IN-14 can be used for research on atopic dermatitis .
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Cat. No.: HY-P70823
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CRLF2; IL-XR; Cytokine Receptor Like Factor 2; Thymic Stromal-Derived Lymphopoietin Receptor; TSLPR; Cytokine Receptor CRL2 Precusor; CRL2; Cytokine Receptor-Like 2; Thymic Stromal Lymphopoietin Protein Receptor; CRLF2Y; Cytokine Receptor-Like Factor 2; P
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P70989
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CRLF2; IL-XR; Cytokine Receptor Like Factor 2; Thymic Stromal-Derived Lymphopoietin Receptor; TSLPR; Cytokine Receptor CRL2 Precusor; CRL2; Cytokine Receptor-Like 2; Thymic Stromal Lymphopoietin Protein Receptor; CRLF2Y; Cytokine Receptor-Like Factor 2; P
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P71389
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CRLF2; IL-XR; Cytokine Receptor Like Factor 2; Thymic Stromal-Derived Lymphopoietin Receptor; TSLPR; Cytokine Receptor CRL2 Precusor; CRL2; Cytokine Receptor-Like 2; Thymic Stromal Lymphopoietin Protein Receptor; CRLF2Y; Cytokine Receptor-Like Factor 2; P
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P700842
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CRLF2; IL-XR; Cytokine Receptor Like Factor 2; Thymic Stromal-Derived Lymphopoietin Receptor; TSLPR; Cytokine Receptor CRL2 Precusor; CRL2; Cytokine Receptor-Like 2; Thymic Stromal Lymphopoietin Protein Receptor; CRLF2Y; Cytokine Receptor-Like Factor 2; P
Species:  
Cynomolgus
Source:  
HEK293
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